Family

GTP cyclohydrolase II, RibA (IPR000926)

Short name: GTP_CycHdrlaseII_RibA

Family relationships

None.

Description

GTP cyclohydrolase II catalyses the first committed step in the biosynthesis of riboflavin. The enzyme converts GTP and water to formate, 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)- pyrimidine and pyrophosphate, and requires magnesium as a cofactor. It is sometimes found as a bifunctional enzyme with 3,4-dihydroxy-2-butanone 4-phosphate synthase (DHBP_synthase) IPR000422.

GO terms

Biological Process

GO:0009231 riboflavin biosynthetic process

Molecular Function

GO:0003935 GTP cyclohydrolase II activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
HAMAP
TIGRFAMs