Family

M-phase inducer phosphatase (IPR000751)

Short name: MPI_Phosphatase

Family relationships

None.

Description

M-phase inducer phosphatases function as dosage-dependent inducers in mitotic control [PMID: 1836978, PMID: 2120044, PMID: 8156993, PMID: 1392080]. They are tyrosine protein phosphatases required for progression of the cell cycle. They may directly dephosphorylate p34(cdc2) and activate p34(cdc2) kinase activity. They catalyse the reaction:

protein tyrosine phosphate + H2O = protein tyrosine + Pi

GO terms

Biological Process

GO:0000087 mitotic M phase
GO:0006470 protein dephosphorylation

Molecular Function

GO:0004725 protein tyrosine phosphatase activity

Cellular Component

GO:0005622 intracellular

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
Pfam