Conserved Site

Type II secretion system protein N, conserved site (IPR000645)

Short name: T2SS_protein-N_CS


The secretion pathway (GSP) for the export of proteins (also called the type II pathway) [PMID: 8438237] requires a number of protein components. One of them is known as the 'N' protein and has been sequenced in a variety of bacteria such as Aeromonas hydrophila (gene exeN); Erwinia carotovora (gene outN); Klebsiella pneumoniae (gene pulN); or Vibrio cholerae (gene epsN). The size of the 'N' protein is around 250 amino acids. It apparently contains a single transmembrane domain located in the N-terminal section. The short N-terminal domain is predicted to be cytoplasmic and the large C-terminal domain periplasmic.

This entry represents a conserved site found towards the N terminus of bacterial type II secretion system protein N.

GO terms

Biological Process

GO:0015628 protein secretion by the type II secretion system

Molecular Function

GO:0008565 protein transporter activity

Cellular Component

GO:0015627 type II protein secretion system complex

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns