Cytochrome c/c1 haem-lyase (IPR000511)

Short name: Cyt_C/C1_haem_lyase

Overlapping homologous superfamilies


Family relationships



Cytochrome c haem-lyase (CCHL) (EC: and cytochrome Cc1 haem-lyase (CC1HL) [PMID: 1499554] are mitochondrial enzymes that catalyse the covalent attachment of a haem group on two cysteine residues of cytochrome c and c1. These two enzymes are functionally and evolutionary related. There are two conserved regions, the first is located in the central section and the second in the C-terminal section. Both patterns contain conserved histidine, tryptophan and acidic residues which could be important for the interaction of the enzymes with the apoproteins and/or the haem group.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0004408 holocytochrome-c synthase activity

Cellular Component

GO:0005739 mitochondrion

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns