Family

Interferon alpha/beta/delta (IPR000471)

Short name: Interferon_alpha/beta/delta

Family relationships

Description

Interferons [PMID: 3022999] are proteins which produce antiviral and antiproliferative responses in cells. On the basis of their sequence interferons are classified into five groups: alpha, alpha-II (or omega), beta, delta (or trophoblast). The sequence differences may possibly cause different responses to various inducers, or result in the recognition of different target cell types [PMID: 6170983]. The main conserved structural feature of interferons is a disulphide bond that, except in mouse beta interferon, occurs in all alpha, beta and omega sequences.

GO terms

Biological Process

GO:0006952 defense response

Molecular Function

GO:0005126 cytokine receptor binding

Cellular Component

GO:0005576 extracellular region

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam
SMART
PROSITE patterns
PRINTS
PANTHER