Neuroligin (IPR000460)

Short name: Nlgn

Overlapping homologous superfamilies

Family relationships


Neuroligins (NLGNs) interact with the neurexin family members and are involved in the modulation of synaptic transmission [PMID: 17275284]. Mammals have four Nlgn proteins, with the Nlgn3 and Nlgn4 gene in humans localised to the X-chromosome. In humans, the Nlgn4 gene is complemented on the Y-chromosome by a similar Nlgn5 gene [PMID: 18923512].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0042043 neurexin family protein binding

Cellular Component

GO:0016020 membrane

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.