Family

Mucin-like glycoprotein (IPR000458)

Short name: Tryp_mucin

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

This family of trypanosomal proteins resemble vertebrate mucins. The protein consists of three regions. The N and C terminii are conserved between all members of the family, whereas the central region is not well conserved and contains a large number of threonine residues which can be glycosylated [PMID: 7592617]. Indirect evidence suggested that these genes might encode the core protein of parasite mucins, glycoproteins that were proposed to be involved in the interaction with, and invasion of, mammalian host cells.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
Pfam