Family

Chorismate synthase (IPR000453)

Short name: Chorismate_synth

Family relationships

None.

Description

Chorismate synthase (EC:4.2.3.5) catalyzes the last of the seven steps in the shikimate pathway which is used in prokaryotes, fungi and plants for the biosynthesis of aromatic amino acids. It catalyzes the 1,4-trans elimination of the phosphate group from 5-enolpyruvylshikimate-3-phosphate (EPSP) to form chorismate which can then be used in phenylalanine, tyrosine or tryptophan biosynthesis. Chorismate synthase requires the presence of a reduced flavin mononucleotide (FMNH2 or FADH2) for its activity. Chorismate synthase from various sources shows a high degree of sequence conservation [PMID: 1718979, PMID: 1837329]. It is a protein of about 360 to 400 amino-acid residues.

GO terms

Biological Process

GO:0009073 aromatic amino acid family biosynthetic process

Molecular Function

GO:0004107 chorismate synthase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
HAMAP
PIRSF
Pfam
PANTHER
TIGRFAMs
SUPERFAMILY
GENE3D