Homologous Superfamily

Nitroreductase-like (IPR000415)

Short name: Nitroreductase-like

Overlapping entries


This domain superfamily is characteristic of nitroreductase enzymes and related oxidoreductases. Members of this family utilise FMN as a cofactor and are often found to be homodimers. Possible characteristics include Oxygen-insensitive NAD(P)H nitroreductase (FMN-dependent nitroreductase) (Dihydropteridine reductase) (EC: and NADH dehydrogenase (EC: A number of the proteins are described as oxidoreductases. They are primarily found in bacterial lineages though a number of eukaryotic homologues have been identified: Caenorhabditis elegans P34273, Drosophila melanogaster (Fruit fly) Q8T3Q0 Q9VTE7, Mus musculus (Mouse) Q9DCX8 and Homo sapiens (Human) O75989. This protein is not found in photosynthetic eukaryotes. The sequences containing this entry in photosynthetic organisms are possible false positives.

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0016491 oxidoreductase activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.