Family

Botulinum neurotoxin/Tetanus toxin (IPR000395)

Short name: Bot/tetX

Overlapping homologous superfamilies

None.

Family relationships

None.

Description

These toxins are zinc proteases that block neurotransmitter release by proteolytic cleavage of synaptic proteins such as synaptobrevins, syntaxin and SNAP-25 [PMID: 8897436, PMID: 7901925].

GO terms

Biological Process

GO:0006508 proteolysis

Molecular Function

GO:0004222 metalloendopeptidase activity
GO:0090729 toxin activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
Pfam