Pathways & interactions
Copper type II, ascorbate-dependent monooxygenase, N-terminal (IPR000323)
Short name: Cu2_ascorb_mOase_N
Copper type II, ascorbate-dependent monooxygenases [PMID: 2792366] are a class of enzymes that requires copper as a cofactor and which uses ascorbate as an electron donor. This family contains two related enzymes, Dopamine-beta-monooxygenase (EC:188.8.131.52) and Peptidyl-glycine alpha-amidating monooxygenase (EC:184.108.40.206). There are a few regions of sequence similarities between these two enzymes, two of these regions contain clusters of conserved histidine residues which are most probably involved in binding copper.
GO:0055114 oxidation-reduction process
GO:0005507 copper ion binding
GO:0004497 monooxygenase activity
GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
No terms assigned in this category.
- PF01082 (Cu2_monooxygen)