Orn/Lys/Arg decarboxylase, major domain (IPR000310)

Short name: Orn/Lys/Arg_deCO2ase_major_dom

Overlapping homologous superfamilies

Domain relationships



Pyridoxal-dependent decarboxylases are bacterial proteins acting on ornithine, lysine, arginine and related substrates [PMID: 8181483]. One of the regions of sequence similarity contains a conserved lysine residue, which is the site of attachment of the pyridoxal-phosphate group. Ornithine decarboxylase is a dodecamer composed of six homodimers and catalyzes the decarboxylation of tryptophan. Arginine decarboxylase catalyzes the decarboxylation of arginine and lysine decarboxylase catalyzes the decarboxylation of lysine. Members of this family are widely found in all three forms of life [PMID: 8181483,PMID: 7663340,PMID: 9405048,PMID: 9063963,PMID: 8112347,PMID: 7748903,PMID: 10586514,PMID: 17504214,PMID: 17109392,PMID: 10223296,PMID: 9914259,PMID: 10800595,PMID: 11933250,PMID: 10673430].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0003824 catalytic activity

Cellular Component

No terms assigned in this category.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns