Conserved Site

D-alanine--D-alanine ligase/VANA/B/C, conserved site (IPR000291)

Short name: D-Ala_lig_Van_CS


D-alanine--D-alanine ligase (EC: is a bacterial enzyme involved in cell-wall biosynthesis. It participates in forming UDP-N-acetylmuramyl pentapeptide, the peptidoglycan precursor. These enzymes are proteins of 300 to 360 amino acids containing many conserved regions. The N-terminal Gly-rich region could be involved in ATP-binding [PMID: 9054558].

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns
PROSITE patterns