Neuraxin/MAP1B repeat (IPR000102)

Short name: MAP1B_neuraxin


In microtubule-associated protein 1B (MAP1B) the basic region containing the KKEE and KKEVI motifs is responsible for the interaction between MAP1B and microtubules in vivo. This region bears no sequence relationship to the microtubule binding domains of kinesin, MAP2, or tau [PMID: 2480963]. Neuraxin is a putative structural protein of the rat central nervous system that is immunologically related to microtubule-associated protein 5 (MAP5). Neuraxin may be implicated in neuronal membrane-microtubule interactions [PMID: 2555150].

Both proteins contain a region that consists of 12 tandem repeats of a 17 residues motif.

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PROSITE patterns