Family

High mobility group nucleosome-binding domain-containing family (IPR000079)

Short name: HMGN_fam

Family relationships

None.

Description

High mobility group nucleosome-binding domain-containing proteins are relatively low molecular weight non-histone components in chromatin. The proteins bind to the inner side of the nucleosomal DNA, altering the interaction between the DNA and the histone octamer. It is thought that they may be involved in the process that confers specific chromatin conformations to transcribable regions in the genome [PMID: 3754870].

GO terms

Biological Process

No terms assigned in this category.

Molecular Function

GO:0031492 nucleosomal DNA binding

Cellular Component

GO:0000785 chromatin
GO:0005634 nucleus

Contributing signatures

Signatures from InterPro member databases are used to construct an entry.
PRINTS
PROSITE patterns
Pfam
PANTHER
SMART