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InterPro: IPR008680 Mastadenovirus early E4 13kDa

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46 proteins

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Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
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Accession

IPR008680 M_adenovirusE4

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF05385	Adeno_E4	46
Signatures in BioMart

InterPro annotation

Entry Details in BioMart

Abstract

This family consists of Homo sapiens and simian mastadenovirus early E4 13 kDa proteins. Human adenovirus 9 (HAdV-9) is unique in eliciting exclusively estrogen-dependent mammary tumours in Rattus spp. and in not requiring viral E1 region transforming genes for tumorigenicity. E4 codes for an oncoprotein essential for tumourigenesis by Ad9 [1].

Database links Help

PANDIT: PF05385

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Example proteins Help

P03240 Probable early E4 13 kDa protein

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Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR008680	Mastadenovirus early E4 13kDa

Publications Open in usermanual
1.	Thomas DL, Schaack J, Vogel H, Javier R. Several E4 region functions influence mammary tumorigenesis by human adenovirus type 9. J. Virol. 75 557-68 2001 [PubMed: 11134268] http://dx.doi.org/10.1128/JVI.75.2.557-568.2001

InterPro 23.1