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InterPro: IPR003176 Viral DNA-binding protein

Protein matches Help

UniProtKB

Matches:

74 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR003176 Vir_DNA_bd

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF02236	Viral_DNA_bi	74
SuperFamily	SSF47724	Vir_DNA_bd	73
Signatures in BioMart

GO Term annotation Help

Process

GO:0006260 DNA replication
GO:0006350 transcription

Function

GO:0003677 DNA binding

Component

GO:0042025 host cell nucleus

InterPro annotation

Entry Details in BioMart

Abstract

This domain represents the C-terminal domain of the viral DNA- binding protein, a multi functional protein involved in DNA replication and transcription control.

Structural links Help

PDB - click here

SCOP: a.54.1.1

CATH: 1.10.269.10

Database links Help

PANDIT: PF02236

CluSTr: ALLvsALL:199269:40.2

Taxonomic coverage Help

Example proteins Help

P03265 Early E2A DNA-binding protein

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR003176	Viral DNA-binding protein
IPR005376	Early E2A, DNA/zinc binding
	PDB Chain
	ModBase
	SCOP Domain
	CATH Domain

Publications Help

Additional Reading Open in usermanual
	Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA. Conformational change of the adenovirus DNA-binding protein induced by soaking crystals with K3UO2F5 solutions. Acta Crystallogr. D Biol. Crystallogr. 52 1996 942-5 [PubMed: 15299602] http://dx.doi.org/10.1107/S0907444996005525
	Kanellopoulos PN, Tsernoglou D, van der Vliet PC, Tucker PA. Alternative arrangements of the protein chain are possible for the adenovirus single-stranded DNA binding protein. J. Mol. Biol. 257 1996 1-8 [PubMed: 8632448] http://dx.doi.org/10.1006/jmbi.1996.0141
	Tucker PA, Tsernoglou D, Tucker AD, Coenjaerts FE, Leenders H, van der Vliet PC. Crystal structure of the adenovirus DNA binding protein reveals a hook-on model for cooperative DNA binding. EMBO J. 13 1994 2994-3002 [PubMed: 8039495] http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=8039495&action=stream&blobtype=pdf

InterPro 23.1