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InterPro: IPR018078 DNA-binding, RecF, conserved site

Protein matches Help

UniProtKB

Matches:

1471 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR018078 DNA-binding_RecF_CS

Type

Conserved_site

Signatures Help

Database	ID	Name	Proteins
PROSITE pattern	PS00617	RECF_1	1262
PROSITE pattern	PS00618	RECF_2	1298
Signatures in BioMart

InterPro Relationships Help

Found in

IPR001238 DNA-binding, RecF
IPR003395 RecF/RecN/SMC protein, N-terminal

GO Term annotation Help

Process

GO:0006281 DNA repair

Function

GO:0003697 single-stranded DNA binding
GO:0005524 ATP binding

InterPro annotation

Entry Details in BioMart

Abstract

All proteins in this family, including RecF, for which functions are known are DNA binding proteins that assist the filamentation of RecA onto DNA for the initiation of recombination or recombinational repair. RecF is involved in DNA metabolism and is required for recombinational DNA repair and for induction of the SOS response [1, 2].

Database links Help

CluSTr: ALLvsALL:30643:40.3

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR018078

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

B0CB57 DNA replication and repair protein recF

P73532 DNA replication and repair protein recF

Q9RVE0 DNA replication and repair protein recF

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR003395	RecF/RecN/SMC protein, N-terminal
IPR003593	ATPase, AAA+ type, core
IPR001238	DNA-binding, RecF
IPR018078	DNA-binding, RecF, conserved site
	SWISS-MODEL
	PDB Chain
	ModBase

Publications Open in usermanual
1.	Alonso JC, Fisher LM. Nucleotide sequence of the recF gene cluster from Staphylococcus aureus and complementation analysis in Bacillus subtilis recF mutants. Mol. Gen. Genet. 246 680-6 1995 [PubMed: 7898435] http://dx.doi.org/10.1007/BF00290713
2.	Sandler SJ, Chackerian B, Li JT, Clark AJ. Sequence and complementation analysis of recF genes from Escherichia coli, Salmonella typhimurium, Pseudomonas putida and Bacillus subtilis: evidence for an essential phosphate binding loop. Nucleic Acids Res. 20 839-45 1992 [PubMed: 1542576] http://dx.doi.org/10.1093/nar/20.4.839

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