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InterPro: IPR017046 Prenylcysteine oxidase

Protein matchesHelp
UniProtKB
Matches:
51 proteins
AccessionHelp IPR017046 Prenylcysteine_Oxase
TypeHelp Family
SignaturesHelp
InterPro RelationshipsHelp
Contains IPR010795 Prenylcysteine lyase
GO Term annotationHelp
Process GO:0055114 oxidation reduction
Function GO:0016670 oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptor
InterPro annotation
BioMart Logo Entry Details in BioMart
AbstractHelp

This entry represents a characterised prenylcysteine oxidase (originally thought to be a prenylcysteine lyase) and homologues that are predicted to have the same function. The human enzyme is part of the lysosome and functions in the degradation of prenylated proteins, cleaving the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine [1].

Database linksHelp
Enzyme: EC:1.8.3

Taxonomic coverageHelp

Overlapping InterPro entriesHelp
IPR017046 Numbers of overlapping proteins Average numbers of overlapping amino acids

Example proteinsHelp
P57681 Probable prenylcysteine oxidase

Q0P5H1 Prenylcysteine oxidase-like

Q8C7K6 Prenylcysteine oxidase-like

Q8NBM8 Prenylcysteine oxidase-like

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR006076 FAD dependent oxidoreductase
IPR010795 Prenylcysteine lyase
IPR017046 Prenylcysteine oxidase
SWISS-MODEL
ModBase

PublicationsHelp
1. Tschantz WR, Zhang L, Casey PJ.
Cloning, expression, and cellular localization of a human prenylcysteine lyase.
J. Biol. Chem. 274 35802-8 1999 [PubMed: 10585463]
http://dx.doi.org/10.1074/jbc.274.50.35802

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InterPro 23.1