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InterPro: IPR016819 Ribonuclease P/MRP protein, subunit Pop5

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UniProtKB

Matches:

37 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR016819 RNase_P/MRP_POP5

Type

Family

Signatures Help

Database	ID	Name	Proteins
PIRSF	PIRSF023803	Ribonuclease_P_prd	37
Signatures in BioMart

InterPro Relationships Help

Parent

IPR002759 Ribonuclease P-related

GO Term annotation Help

Process

GO:0016070 RNA metabolic process

Function

GO:0004526 ribonuclease P activity

Component

GO:0005634 nucleus

InterPro annotation

Entry Details in BioMart

Abstract

This entry represents the Pop5 subunit found in ribonulcease (RNase) P (EC:3.1.26.5) and RNase MRP, both ribonucleases functioning as endoribonucleases [1]. RNase P is a protein complex that functions in the processing of pre-tRNA, generating mature tRNA molecules by cleaving their 5'-ends; it consists of a RNA moiety and at least 8 protein subunits (Pop1, Rpp14, Rpp20/Pop7, Rpp25, Rpp29/Pop4, Rpp30, Rpp38 and Rpp40). RNase MRP has been implicated in the processing of precursor-rRNA; it consists of a RNA moiety and at least 10 protein subunits (Pop1, Rpp14, Rpp20/Pop7, Rpp25, Rpp29/Pop4, Rpp30, Rpp38, Rpp40, Pop5 and Rpp21).

Database links Help

Enzyme: EC:3.1.26.5

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR016819

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

Q1JQ92 Ribonuclease P/MRP protein subunit POP5

Q54EP3 Probable ribonuclease P/MRP protein subunit POP5

Q969H6 Ribonuclease P/MRP protein subunit POP5

Q9DB28 Ribonuclease P/MRP protein subunit POP5

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR016819	Ribonuclease P/MRP protein, subunit Pop5
IPR002759	Ribonuclease P-related
	SWISS-MODEL
	ModBase

Publications Open in usermanual
1.	van Eenennaam H, Lugtenberg D, Vogelzangs JH, van Venrooij WJ, Pruijn GJ. hPop5, a protein subunit of the human RNase MRP and RNase P endoribonucleases. J. Biol. Chem. 276 31635-41 2001 [PubMed: 11413139] http://dx.doi.org/10.1074/jbc.M103399200

InterPro 23.1