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InterPro: IPR016040 NAD(P)-binding domain

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UniProtKB
Matches:
212210 proteins
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IPR016040 NAD(P)-bd_dom
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Domain
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InterPro RelationshipsHelp
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Children IPR000534 Semialdehyde dehydrogenase, NAD-binding
IPR000669 Mannitol dehydrogenase, core
IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal
IPR002225 3-beta hydroxysteroid dehydrogenase/isomerase
IPR003781 CoA-binding
IPR003869 Polysaccharide biosynthesis protein CapD-like
IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding
IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal
IPR006115 6-phosphogluconate dehydrogenase, NAD-binding
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding
IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase
IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding
IPR007698 Alanine dehydrogenase/PNT, C-terminal
IPR011128 NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal
IPR012302 Malic enzyme, NAD-binding
IPR013116 Acetohydroxy acid isomeroreductase, catalytic
IPR013120 Male sterility, NAD-binding
IPR013149 Alcohol dehydrogenase, zinc-binding
IPR013332 Ketopantoate reductase ApbA/PanE, N-terminal
IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal
IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding
IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain
IPR019901 Ergot alkaloid biosynthesis protein
IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR020842 Polyketide synthase/Fatty acid synthase, KR
Found in IPR000043 S-adenosyl-L-homocysteine hydrolase
IPR000173 Glyceraldehyde 3-phosphate dehydrogenase subfamily
IPR000304 Delta 1-pyrroline-5-carboxylate reductase
IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase
IPR000846 Dihydrodipicolinate reductase
IPR001088 Glycoside hydrolase, family 4
IPR001236 Lactate/malate dehydrogenase
IPR001282 Glucose-6-phosphate dehydrogenase
IPR001509 NAD-dependent epimerase/dehydratase
IPR001557 L-lactate/malate dehydrogenase
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR002424 Insect alcohol dehydrogenase family
IPR002425 Insect alcohol dehydrogenase
IPR002426 Ceratitis capitata alcohol dehydrogenase
IPR002427 Alcohol dehydrogenase-related protein
IPR002587 Myo-inositol-1-phosphate synthase
IPR003099 Prephenate dehydrogenase
IPR003462 Ornithine cyclodeaminase/mu-crystallin
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR003929 Potassium channel, calcium-activated, BK, alpha subunit
IPR004432 Polyketide-type polyunsaturated fatty acid synthase, PfaA
IPR004455 NADP oxidoreductase, coenzyme F420-dependent
IPR004627 L-threonine 3-dehydrogenase
IPR005097 Saccharopine dehydrogenase
IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase
IPR005886 UDP-glucose 4-epimerase
IPR005888 dTDP-glucose 4,6-dehydratase
IPR005913 dTDP-4-dehydrorhamnose reductase
IPR005979 Light-dependent protochlorophyllide reductase
IPR006036 Potassium uptake protein TrkA
IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IPR006277 Sarcosine oxidase, alpha subunit, heterotetrameric
IPR006367 Sirohaem synthase, N-terminal
IPR006368 GDP-mannose 4,6-dehydratase
IPR006393 Sepiapterin reductase
IPR006422 D-erythrose-4-phosphate dehydrogenase
IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II
IPR007780 Bacterial NAD-glutamate dehydrogenase
IPR008030 NmrA-like
IPR008089 Nucleotide sugar epimerase
IPR008244 Bifunctional chorismate mutase/prephenate dehydrogenase T-protein
IPR008289 Pentafunctional AroM protein
IPR008299 Prephenate dehydrogenase/arogenate dehydrogenase predicted, C-terminal regulatory region-containing
IPR008354 Glucose-fructose oxidoreductase, bacterial
IPR010062 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase
IPR010063 Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related
IPR010091 Thiazolinyl imide reductase
IPR010097 Malate dehydrogenase, NAD-dependent, eukaryote/gamma proteobacteria
IPR010099 Sugar nucleotide epimerase YfcH, putative
IPR010185 NADPH-dependent F420 reductase
IPR010190 Diaminopimelate dehydrogenase
IPR010420 Protein of unknown function DUF1012
IPR010429 Bacterial FdrA
IPR010945 Malate dehydrogenase, NAD/NADP
IPR011182 Aspartate dehydrogenase, NAD biosynthesis
IPR011272 Lactate dehydrogenase
IPR011273 Malate dehydrogenase, NADP-dependent, plants
IPR011274 Malate dehydrogenase, NAD-dependent, cytosolic
IPR011275 Malate dehydrogenase, NAD-dependent
IPR011283 Acetoacetyl-CoA reductase
IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase
IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative
IPR011286 2-deoxy-D-gluconate 3-dehydrogenase
IPR011294 3-hydroxybutyrate dehydrogenase
IPR011304 L-lactate dehydrogenase
IPR011348 17beta-dehydrogenase
IPR011770 Dihydrodipicolinate reductase, bacterial/plant
IPR011859 Dihydrodipicolinate reductase, plant
IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase
IPR012066 Uroporphyrin-III C-methyltransferase, yeast
IPR012070 Arogenate/prephenate dehydrogenase, plant
IPR012115 Bifunctional ribulose 5-phosphate reductase/CDP-ribitol pyrophosphorylase
IPR012385 Prephenate dehydrogenase, fungal
IPR012742 Alanine dehydrogenase, archaea
IPR012799 Fatty oxidation complex, alpha subunit FadB
IPR013445 CDP-glucose 4,6-dehydratase
IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase
IPR013952 Protein of unknown function DUF1776, fungi
IPR014007 Acetoin reductase
IPR014058 Pteridine reductase
IPR014308 Xanthine dehydrogenase accessory protein XdhC
IPR014334 Ectoine utilization protein EutC
IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH)
IPR015845 Agropine synthesis reductase
IPR016836 Uncharacterised conserved protein UCP026396, short chain dehydrogenase, Alr5284
IPR017094 Biliverdin reductase A
IPR017619 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase
IPR017701 Putative selenate reductase YgfK
IPR017711 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria
IPR017829 Hopanoid-associated sugar epimerase
IPR018075 Ubiquitin-activating enzyme, E1
IPR020626 Aspartate dehydrogenase, NAD biosynthesis, prokaryotic
IPR020831 Glyceraldehyde 3-phosphate dehydrogenase family
IPR020843 Polyketide synthase, enoylreductase
IPR020884 Glutathione-regulated potassium-efflux system protein KefB
IPR020921 Erythronate-4-phosphate dehydrogenase
Contains IPR000683 Oxidoreductase, N-terminal
IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site
IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site
IPR003148 Regulator of K+ conductance, N-terminal
IPR006037 Regulator of K+ conductance, C-terminal
IPR006181 D-amino acid oxidase, conserved site
IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2
IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like
IPR013131 Mannitol dehydrogenase, N-terminal
IPR013549 Domain of unknown function DUF1731, C-terminal
IPR015884 Malic enzyme, conserved site
IPR018074 Ubiquitin-activating enzyme, E1, active site
IPR019572 Ubiquitin-activating enzyme
IPR019796 Glucose-6-phosphate dehydrogenase, active site
IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site
IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site
IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site
IPR020904 Short-chain dehydrogenase/reductase, conserved site
GO Term annotationHelp
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Process GO:0008152 metabolic process
Function GO:0003824 catalytic activity
GO:0005488 binding
InterPro annotation
BioMart Logo Entry Details in BioMart
AbstractHelp
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This entry represents NAD- and NADP-binding domains with a core Rossmann-type fold, which consists of 3-layers alpha/beta/alpha, where the six beta strands are parallel in the order 321456. Many different enzymes contain an NAD/NADP-binding domain, including:

  • C-terminal domain of alcohol dehydrogenases [1]
  • Tyrosine-dependent oxidoreductases (also known as short-chain dehydrogenases) [2]
  • N-terminal domain of glyceraldehyde-3-phosphate dehydrogenase [3]
  • NAD-binding domain of formate/glycerate dehydrogenases [4]
  • N-terminal domain of sirohaem synthase [5]
  • N-terminal domain of lactate dehydrogenase [6]
  • N-terminal domain of 6-phosphogluconate dehydrogenase (the beta-sheet is extended to 8 strands) [7]
  • C-terminal domain of amino acid dehydrogenases (an extra N-terminal helix displaces the C-terminal helix [8]
  • NAD-binding domain of certain potassium channels [9]
  • C-terminal domain of the transcriptional repressor Rex [10]
  • Ornithine cyclodeaminase [11]
  • CoA-binding N-terminal domain of the alpha chain of succinyl-CoA synthetase [12]
Structural linksHelp
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PDB - click here
1a27 , 1a4i , 1a4u , 1a5z , 1a71 , 1a72 , 1a7a , 1a7k , 1a9y , 1a9z , 1adb , 1adc , 1adf , 1adg , 1ae1 , 1agn , 1ahh , 1ahi , 1an9 , 1arz , 1aup , 1axe , 1axg , 1b0a , 1b14 , 1b15 , 1b16 , 1b26 , 1b2l , 1b3b , 1b3r , 1b7g , 1b8p , 1b8u , 1b8v , 1bdb , 1bdm , 1bg6 , 1bgv , 1bhs , 1bmd , 1brm , 1bsv , 1bto , 1bvr , 1bvu , 1bw9 , 1bws , 1bxg , 1bxk , 1bxz , 1c0i , 1c0k , 1c0l , 1c0p , 1c14 , 1c1d , 1c1x , 1c3v , 1cdo , 1ceq , 1cer , 1cet , 1cf2 , 1civ , 1cqi , 1cqj , 1crw , 1cwu , 1cyd , 1d1s , 1d1t , 1d3a , 1d4f , 1d7o , 1d8a , 1dao , 1dap , 1db3 , 1dbv , 1dc3 , 1dc4 , 1dc5 , 1dc6 , 1ddo , 1deh , 1dfg , 1dfh , 1dfi , 1dhr , 1dht , 1dia , 1dib , 1dig , 1dih , 1dir , 1dli , 1dlj , 1do8 , 1doh , 1dpg , 1dru , 1drv , 1drw , 1dss , 1dxy , 1e0d , 1e3e , 1e3i , 1e3j , 1e3l , 1e3s , 1e3w , 1e5l , 1e5q , 1e6u , 1e6w , 1e77 , 1e7m , 1e7q , 1e7r , 1e7s , 1e7w , 1e7y , 1e92 , 1ebf , 1ebu , 1edo , 1edz , 1ee2 , 1ee9 , 1eeh , 1efk , 1efl , 1ek5 , 1ek6 , 1emd , 1eno , 1enp , 1eny , 1enz , 1eq2 , 1equ , 1euc , 1eud , 1euz , 1evi , 1evj , 1evy , 1evz , 1ez4 , 1f06 , 1f0y , 1f12 , 1f14 , 1f17 , 1f8f , 1f8g , 1fds , 1fdt , 1fdu , 1fdv , 1fdw , 1ff9 , 1fjh , 1fk8 , 1fmc , 1fxs , 1g0n , 1g0o , 1g1a , 1g6k , 1gad , 1gae , 1gco , 1gcu , 1gd1 , 1gdh , 1gee , 1geg , 1gfs , 1gga , 1gl3 , 1gpd , 1gpj , 1gq2 , 1gqq , 1gqy , 1gr0 , 1gt2 , 1gt8 , 1gte , 1gth , 1gtm , 1gu7 , 1guf , 1guy , 1guz , 1gv0 , 1gv1 , 1gy8 , 1gyp , 1gyq , 1gyr , 1gz3 , 1gz4 , 1gz6 , 1h0k , 1h2b , 1h2h , 1h5q , 1h6a , 1h6b , 1h6c , 1h6d , 1h7w , 1h7x , 1h93 , 1h94 , 1h9a , 1h9b , 1hdc , 1hdg , 1hdo , 1hdr , 1hdx , 1hdy , 1hdz , 1he2 , 1he3 , 1he4 , 1he5 , 1het , 1heu , 1hf3 , 1hku , 1hl3 , 1hld , 1hlp , 1hrd , 1hso , 1hsz , 1ht0 , 1htb , 1hwx , 1hwy , 1hwz , 1hxh , 1hye , 1hyg , 1hyh , 1hzj , 1hzz , 1i01 , 1i0z , 1i10 , 1i24 , 1i2b , 1i2c , 1i2z , 1i30 , 1i32 , 1i33 , 1i36 , 1i3k , 1i3l , 1i3m , 1i3n , 1i5r , 1i8t , 1ib6 , 1id1 , 1ie3 , 1ihx , 1ihy , 1il0 , 1iol , 1ipe , 1ipf , 1isf , 1isg , 1ish , 1isi , 1isj , 1ism , 1iuk , 1iul , 1iy8 , 1iyz , 1iz0 , 1iz9 , 1j0x , 1j49 , 1j4a , 1j5p , 1j6u , 1ja9 , 1jax , 1jay , 1jdj , 1jkf , 1jki , 1jkj , 1jll , 1jn0 , 1jqb , 1jtv , 1ju9 , 1jvb , 1jvs , 1jw9 , 1jwa , 1jwb , 1k0u , 1k2w , 1k3t , 1k5h , 1k6i , 1k6j , 1k6x , 1k89 , 1kbz , 1kc1 , 1kc3 , 1kep , 1ker , 1ket , 1keu , 1kev , 1kew , 1kif , 1kol , 1ks9 , 1kvq , 1kvr , 1kvs , 1kvt , 1kvu , 1ky4 , 1ky5 , 1kyq , 1l1f , 1l7d , 1l7e , 1la2 , 1lbe , 1lc0 , 1lc3 , 1ldb , 1lde , 1ldg , 1ldm , 1ldn , 1ldy , 1leh , 1li4 , 1lj8 , 1llc , 1lld , 1llq , 1llu , 1lnq , 1lrj , 1lrk , 1lrl , 1lsj , 1lso , 1lss , 1lsu , 1lth , 1lu9 , 1lua , 1lx6 , 1lxc , 1m2w , 1m66 , 1m67 , 1m6h , 1m6w , 1m75 , 1m76 , 1ma0 , 1mb4 , 1mc4 , 1mc5 , 1mfp , 1mfz , 1mg0 , 1mg5 , 1mgo , 1ml3 , 1mld , 1mp0 , 1muu , 1mv8 , 1mx3 , 1mxf , 1mxh , 1n1e , 1n1g , 1n2s , 1n5d , 1n7g , 1n7h , 1n8k , 1n92 , 1n9g , 1nah , 1nai , 1nas , 1nbo , 1nff , 1nfq , 1nfr , 1nhg , 1nhw , 1nm5 , 1nnu , 1np3 , 1npd , 1npt , 1npy , 1nq5 , 1nqa , 1nqo , 1nqt , 1nr1 , 1nr7 , 1nto , 1nvg , 1nvm , 1nvt , 1nwc , 1nwh , 1nx6 , 1nxq , 1nyt , 1o0s , 1o5i , 1o6z , 1o89 , 1o8c , 1o9b , 1oaa , 1obb , 1obf , 1oc2 , 1oc4 , 1ofg , 1oi7 , 1ojs , 1oju , 1omo , 1onn , 1ono , 1onp , 1ooe , 1orr , 1oza , 1p0c , 1p0f , 1p1f , 1p1h , 1p1i , 1p1j , 1p1k , 1p1r , 1p31 , 1p33 , 1p3d , 1p44 , 1p45 , 1p74 , 1p77 , 1p9l , 1ped , 1pgj , 1pgn , 1pgo , 1pgp , 1pgq , 1piw , 1pj2 , 1pj3 , 1pj4 , 1pjb , 1pjc , 1pjl , 1pjq , 1pjs , 1pjt , 1pl6 , 1pl7 , 1pl8 , 1pqp , 1pqu , 1pqw , 1pr3 , 1pr9 , 1ps0 , 1ps8 , 1psd , 1ptj , 1pu2 , 1pwx , 1pwz , 1px0 , 1pze , 1pzf , 1pzg , 1pzh , 1q0h , 1q0l , 1q0q , 1q1n , 1q2x , 1q7b , 1q7c , 1q7g , 1qg6 , 1qki , 1qlh , 1qlj , 1qmg , 1qor , 1qp8 , 1qr6 , 1qrr , 1qsg , 1qv6 , 1qv7 , 1qxs , 1qyc , 1qyd , 1qyv , 1qyw , 1qyx , 1r0k , 1r0l , 1r0s , 1r12 , 1r15 , 1r16 , 1r37 , 1r4m , 1r4n , 1r66 , 1r6d , 1rjw , 1rkx , 1rm0 , 1rm3 , 1rm4 , 1rm5 , 1rpn , 1rwb , 1ryd , 1rye , 1s6y , 1s7c , 1say , 1sb8 , 1sb9 , 1sby , 1sc6 , 1scu , 1sep , 1sev , 1smk , 1sny , 1so8 , 1sov , 1sow , 1spx , 1szj , 1t1r , 1t1s , 1t24 , 1t25 , 1t26 , 1t2a , 1t2c , 1t2d , 1t2e , 1t2f , 1t4b , 1t4d , 1ta4 , 1tb4 , 1teh , 1ti7 , 1tlt , 1tt5 , 1tt7 , 1tve , 1txg , 1u1i , 1u28 , 1u2d , 1u2g , 1u3t , 1u3u , 1u3v , 1u3w , 1u4o , 1u4s , 1u5a , 1u5c , 1u7h , 1u7t , 1u8f , 1u8x , 1u9j , 1uag , 1uay , 1uda , 1udb , 1udc , 1uh5 , 1ujm , 1uls , 1ulu , 1up4 , 1up6 , 1up7 , 1ur5 , 1uuf , 1uxg , 1uxh , 1uxi , 1uxj , 1uxk , 1uzl , 1uzm , 1uzn , 1v35 , 1v3t , 1v3u , 1v3v , 1v6a , 1v8b , 1v9l , 1vc2 , 1vct , 1ve9 , 1vi2 , 1vj0 , 1vj1 , 1vkn , 1vko , 1vl0 , 1vl6 , 1vl8 , 1vll , 1vm6 , 1vpd , 1vrw , 1w0c , 1w4z , 1w6u , 1w73 , 1w8d , 1wam , 1wdk , 1wdl , 1wdm , 1wly , 1wma , 1wmb , 1wnt , 1wp4 , 1wvg , 1wze , 1wzi , 1x1e , 1x1t , 1x7d , 1x7g , 1x7h , 1xcb , 1xea , 1xel , 1xg5 , 1xgk , 1xhc , 1xhl , 1xiv , 1xkq , 1xlt , 1xq1 , 1xq6 , 1xr3 , 1xse , 1xu7 , 1xu9 , 1xwf , 1xyg , 1y1p , 1y5m , 1y5r , 1y6j , 1y7t , 1y81 , 1y8q , 1y8r , 1y8x , 1y9a , 1y9e , 1yb1 , 1yb4 , 1yb5 , 1yba , 1ybm , 1ybv , 1yde , 1ydw , 1ye3 , 1ygy , 1yjq , 1ykf , 1yl5 , 1yl6 , 1yl7 , 1yo6 , 1yon , 1yov , 1yqd , 1yqg , 1yqx , 1yve , 1ywg , 1yxm , 1z45 , 1z6z , 1z73 , 1z74 , 1z75 , 1z7b , 1z7e , 1zbq , 1zem , 1zfn , 1zh8 , 1zid , 1zjy , 1zjz , 1zk0 , 1zk1 , 1zk2 , 1zk3 , 1zk4 , 1zkm , 1zmt , 1znq , 1zo8 , 1zsn , 1zsv , 1zud , 1zw1 , 1zxb , 1zxl , 1zze , 2a35 , 2a92 , 2a94 , 2aa3 , 2ae1 , 2ae2 , 2ag5 , 2ag8 , 2ahr , 2amf , 2aq8 , 2aqh , 2aqi , 2aqk , 2aw5 , 2b0j , 2b35 , 2b36 , 2b37 , 2b4q , 2b4r , 2b4t , 2b69 , 2b83 , 2bd0 , 2bel , 2bf7 , 2bfa , 2bfm , 2bfo , 2bfp , 2bgk , 2bgl , 2bgm , 2bh9 , 2bhl , 2bi7 , 2bi8 , 2bka , 2bkn , 2bko , 2bkp , 2bll , 2c07 , 2c20 , 2c54 , 2c59 , 2c5a , 2c5e , 2c7v , 2cf5 , 2cf6 , 2cfc , 2cmd , 2cnb , 2csu , 2cvo , 2cvq , 2cvz , 2czc , 2d1y , 2d2i , 2d3t , 2d4a , 2d59 , 2d5a , 2dap , 2dbv , 2dc1 , 2dfd , 2dkn , 2dld , 2dm6 , 2dpg , 2dph , 2dt5 , 2du8 , 2duw , 2e37 , 2e48 , 2e49 , 2e4a , 2e6u , 2e82 , 2eer , 2ef1 , 2egg , 2egh , 2ekp , 2ekq , 2ew8 , 2ewd , 2ewm , 2f00 , 2f1k , 2fhs , 2fm3 , 2fmu , 2fn7 , 2fnz , 2fp4 , 2fpg , 2fpi , 2fpp , 2fr0 , 2fr1 , 2fr8 , 2frd , 2frm , 2fsv , 2fy8 , 2fze , 2fzw , 2g17 , 2g5c , 2g82 , 2gcg , 2gd1 , 2gdz , 2gf2 , 2go1 , 2gsd , 2gug , 2gyy , 2gz1 , 2gz2 , 2gz3 , 2h1s , 2h5l , 2h63 , 2h6e , 2h7i , 2h7l , 2h7m , 2h7n , 2h7p , 2h9i , 2hae , 2hcy , 2hdh , 2hjr , 2hjs , 2hk7 , 2hk8 , 2hk9 , 2hki , 2hlp , 2hms , 2hmt , 2hmu , 2hmv , 2hmw , 2ho3 , 2ho5 , 2hrb , 2hsd , 2hu2 , 2hun , 2i9p , 2idz , 2ie0 , 2ieb , 2ied , 2irw , 2ivd , 2ive , 2iyo , 2iyp , 2iz0 , 2iz1 , 2j3h , 2j3i , 2j3j , 2j3k , 2j5k , 2j5q , 2j5r , 2jff , 2jfg , 2jfh , 2jhf , 2jhg , 2ldb , 2ldx , 2nac , 2nad , 2nm0 , 2nq8 , 2nsd , 2ntj , 2ntn , 2ntv , 2nu6 , 2nu7 , 2nu8 , 2nu9 , 2nua , 2nv6 , 2nvb , 2nvu , 2nvw , 2o23 , 2o2s , 2o2y , 2o3j , 2o50 , 2ofp , 2ohx , 2ol4 , 2ome , 2oo5 , 2oor , 2oos , 2op0 , 2op1 , 2oui , 2oxi , 2p2s , 2p4q , 2p5u , 2p5y , 2p68 , 2p91 , 2p9c , 2p9e , 2p9g , 2pa3 , 2pd3 , 2pd4 , 2pd6 , 2pfg , 2pgd , 2ph3 , 2pkq , 2pkr , 2pnf , 2pr2 , 2pv7 , 2pwz , 2q2q , 2q2v , 2q2w , 2q3e , 2q45 , 2q46 , 2q49 , 2q4b , 2q4e , 2q50 , 2qg4 , 2qhx , 2rbe , 2rh4 , 2rhc , 2scu , 2tmg , 2uag , 2udp , 2uuo , 2uup , 2uvd , 2v6b , 2v6m , 2v7p , 2vus , 2vut , 2vuu , 2vyn , 2vyv , 2yv1 , 2yv2 , 2yw9 , 2yyy , 2z1m , 2z1n , 2z95 , 2zat , 3bhi , 3bhj , 3bhm , 3bto , 3byz , 3bzu , 3cin , 3cmc , 3cos , 3cum , 3czr , 3d3e , 3d4n , 3d5q , 3dap , 3dbh , 3dbl , 3dbr , 3dbv , 3dhe , 3dmt , 3e1k , 3gpd , 3had , 3hdh , 3hud , 3ldh , 3uag , 4dbv , 4gpd , 4mdh , 4uag , 5adh , 5ldh , 5mdh , 6adh , 6ldh , 7adh , 7mdh , 8adh , 8ldh , 9ldb , 9ldt

Taxonomic coverageHelp
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Overlapping InterPro entriesHelp
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IPR016040 Numbers of overlapping proteins Average numbers of overlapping amino acids

Example proteinsHelp
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O14556 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

P00330 Alcohol dehydrogenase 1

P00334 Alcohol dehydrogenase

P00342 L-lactate dehydrogenase C chain

Q19905 UDP-glucose 6-dehydrogenase

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR020904 Short-chain dehydrogenase/reductase, conserved site
IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain
IPR013149 Alcohol dehydrogenase, zinc-binding
IPR001236 Lactate/malate dehydrogenase
IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain
IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I
IPR001557 L-lactate/malate dehydrogenase
IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal
IPR002198 Short-chain dehydrogenase/reductase SDR
IPR011032 GroES-like
IPR016040 NAD(P)-binding domain
IPR018177 L-lactate dehydrogenase, active site
IPR013154 Alcohol dehydrogenase GroES-like
IPR014028 UDP-glucose/GDP-mannose dehydrogenase, dimerisation and substrate-binding domain
IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal
IPR002085 Alcohol dehydrogenase superfamily, zinc-containing
IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation
IPR020831 Glyceraldehyde 3-phosphate dehydrogenase family
IPR011304 L-lactate dehydrogenase
IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site
IPR017476 Nucleotide sugar dehydrogenase
IPR002424 Insect alcohol dehydrogenase family
IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR020832 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain, subgroup
IPR002328 Alcohol dehydrogenase, zinc-containing, conserved site
IPR002425 Insect alcohol dehydrogenase
IPR008927 6-phosphogluconate dehydrogenase, C-terminal-like
IPR000173 Glyceraldehyde 3-phosphate dehydrogenase subfamily
ModBase
PDB Chain
CATH Domain
SCOP Domain

PublicationsHelp
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1. Gibbons BJ, Hurley TD.
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Open in usermanual
Kawakami R, Sakuraba H, Goda S, Tsuge H, Ohshima T.
Refolding, characterization and crystal structure of (S)-malate dehydrogenase from the hyperthermophilic archaeon Aeropyrum pernix.
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Frayne J, Taylor A, Cameron G, Hadfield AT.
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Crystal structure of a 3-oxoacyl-(acylcarrier protein) reductase (BA3989) from Bacillus anthracis at 2.4-A resolution.
Proteins 70 2008 562-7 [PubMed: 17894349]
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X-Ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.
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Thermal stabilization of the protozoan Entamoeba histolytica alcohol dehydrogenase by a single proline substitution.
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http://dx.doi.org/10.1002/prot.21946
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