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InterPro: IPR013783 Immunoglobulin-like fold

Protein matchesHelp
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UniProtKB
Matches:
28078 proteins
AccessionHelp
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IPR013783 Ig-like_fold
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Domain
SignaturesHelp
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InterPro RelationshipsHelp
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Children IPR001102 Transglutaminase, N-terminal
Found in IPR000451 NF-kappa-B/Rel/dorsal
IPR006407 1,4-alpha-glucan branching enzyme, core region
IPR008291 Glucan 1,4-alpha-glucosidase, starch-binding
IPR008366 Nuclear factor of activated T cells (NFAT)
IPR008465 Dystroglycan
IPR009134 Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal
IPR009136 Tyrosine-protein kinase, vascular endothelial growth factor receptor 2 (VEGFR2)
IPR011363 Dorsal protein
IPR011837 Glycogen debranching enzyme GlgX
IPR011838 Pullulanase, extracellular
IPR011840 Pullulanase, type I
IPR012768 Malto-oligosyltrehalose trehalohydrolase
IPR013540 Chitinase A N-terminal
IPR015171 Cyclomaltodextrinase, N-terminal
IPR015202 Domain of unknown function DUF1929
IPR015468 CD8 alpha subunit
IPR015477 CD3 epsilon chain
IPR015484 CD3 protein, gamma/delta subunit
IPR015485 CD3 signaling complex delta subunit
IPR015528 Interleukin-12 beta chain
IPR015621 Interleukin-1 receptor
IPR015646 Nuclear factor of activated T-cells 5
IPR015647 Nuclear factor of activated T-cells 1
IPR015651 CD86 T cell co-stimulatory antigen
IPR015653 Intercellular adhesion molecule 2
IPR015707 Beta-2-Microglobulin
IPR015714 Lymphocyte function associated antigen 3
IPR015725 Myosin light chain kinase
IPR015726 Serine/threonine protein kinase, striated muscle-specific
IPR015775 Tyrosine-protein kinase, receptor Axl-related
IPR015776 Tyrosine-protein kinase, platelet-derived growth factor receptor alpha
IPR015781 Tyrosine-protein kinase, angiopoietin receptor
IPR016243 Tyrosine-protein kinase, CSF-1/PDGF receptor
IPR016247 Tyrosine-protein kinase, receptor ROR, subgroup
IPR016248 Tyrosine-protein kinase, fibroblast growth factor receptor
IPR016332 Alpha-1B-glycoprotein/leukocyte immunoglobulin-like receptor
IPR016663 Myelin-oligodendrocyte glycoprotein
IPR018286 Nuclear factor of activated T cells (NFAT), subgroup
IPR020426 Tyrosine-protein kinase, neurotrophic receptor, N-terminal region
IPR020446 Tyrosine-protein kinase, neurotrophic receptor, type 3, N-terminal region
IPR020455 Tyrosine-protein kinase, neurotrophic receptor, type 2, N-terminal region
IPR020675 Myosin light chain kinase-related
IPR020678 Nexilin
IPR020696 Tyrosine-protein kinase, receptor Tie-1
IPR020704 Tyrosine-protein kinase, receptor TYRO3, Zebrafish
IPR020705 Tyrosine-protein kinase, receptor MER
IPR020716 Tyrosine-protein kinase, muscle/skeletal receptor
IPR020718 Tyrosine-protein kinase, PDGF/VEGF receptor, fly
IPR020721 Tyrosine-protein kinase, vascular endothelial growth factor receptor 3 (VEGFR3)
IPR020722 Tyrosine-protein kinase, vascular endothelial growth factor receptor 1 (VEGFR1)
IPR020725 Tyrosine-protein kinase, myoblast growth factor receptor Egl-15
IPR020727 Tyrosine-protein kinase, platelet-derived growth factor receptor beta
IPR020729 Tyrosine-protein kinase, macrophage colony-stimulating factor 1 receptor
IPR020730 Tyrosine-protein kinase, mast/stem cell growth factor receptor
IPR020732 Tyrosine-protein kinase, fibroblast growth factor receptor-related
IPR020741 Tyrosine-protein kinase, receptor TYRO3
IPR020763 Tyrosine-protein kinase, receptor ROR
IPR020774 Tyrosine-protein kinase, receptor PTK7
IPR020777 Tyrosine-protein kinase, neurotrophic receptor
Contains IPR000973 T-cell surface antigen CD4
IPR001298 Filamin/ABP280 repeat
IPR002044 Glycoside hydrolase, carbohydrate-binding
IPR002909 Cell surface receptor IPT/TIG
IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
IPR003987 Intercellular adhesion molecule/vascular cell adhesion molecule, N-terminal
IPR003988 Intercellular adhesion molecule
IPR004193 Glycoside hydrolase, family 13, N-terminal
IPR004197 Glycoside hydrolase, family 9, N-terminal, Ig-like
IPR005102 Protein of unknown function DUF291
IPR005536 Peptidase C25, C-terminal Ig-like domain
IPR007110 Immunoglobulin-like
IPR008424 Immunoglobulin C2-set
IPR013285 T-cell surface antigen CD2
IPR013768 Intercellular adhesion molecule, N-terminal
IPR015169 Adhesion molecule, immunoglobulin-like
IPR015274 CD4, extracellular
IPR015370 Protein of unknown function DUF1968
IPR017868 Filamin/ABP280 repeat-like
InterPro annotation
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This entry represents domains with an immunoglobulin-like (Ig-like) fold, which consists of a beta-sandwich of seven or more strands in two sheets with a Greek-key topology. Ig-like domains are one of the most common protein modules found in animals, occurring in a variety of different proteins. These domains are often involved in interactions, commonly with other Ig-like domains via their beta-sheets [1, 2, 3, 4]. Domains within this fold-family share the same structure, but can diverge with respect to their sequence. Based on sequence, Ig-like domains can be classified as V-set domains (antibody variable domain-like), C1-set domains (antibody constant domain-like), C2-set domains, and I-set domains (antibody intermediate domain-like). Proteins can contain more than one of these types of Ig-like domains. For example, in the human T-cell receptor antigen CD2, domain 1 (D1) is a V-set domain, while domain 2 (D2) is a C2-set domain, both domains having the same Ig-like fold [5].

Domains with an Ig-like fold can be found in many, diverse proteins in addition to immunoglobulin molecules. For example, Ig-like domains occur in several different types of receptors (such as various T-cell antigen receptors), several cell adhesion molecules, MHC class I and II antigens, as well as the hemolymph protein hemolin, and the muscle proteins titin, telokin and twitchin.

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15c8 , 1a02 , 1a14 , 1a1m , 1a1n , 1a1o , 1a2y , 1a3q , 1a3r , 1a47 , 1a4j , 1a4k , 1a64 , 1a66 , 1a6a , 1a6p , 1a6u , 1a6v , 1a6w , 1a6z , 1a7b , 1a7n , 1a7o , 1a7p , 1a7r , 1a8j , 1a9b , 1a9e , 1ac0 , 1ac6 , 1acy , 1acz , 1adq , 1ae6 , 1agb , 1agc , 1agd , 1age , 1agf , 1ah1 , 1ai1 , 1aif , 1aj7 , 1akj , 1ao7 , 1aqd , 1aqk , 1ar1 , 1ar2 , 1axs , 1axt , 1b0g , 1b0r , 1b0w , 1b3j , 1b6u , 1b88 , 1b90 , 1b9z , 1bbj , 1bd2 , 1bf2 , 1bfs , 1bft , 1bih , 1bii , 1bj8 , 1bmg , 1bog , 1bpv , 1bqh , 1bqs , 1bqu , 1bvz , 1bwm , 1bww , 1bx2 , 1bz9 , 1c08 , 1c16 , 1ccz , 1cd0 , 1cd1 , 1cd8 , 1cdb , 1cdc , 1cdg , 1cdh , 1cdi , 1cdj , 1cdu , 1cdy , 1ce1 , 1ce6 , 1cg9 , 1cgt , 1cgu , 1cgv , 1cgw , 1cgx , 1cgy , 1ci5 , 1cic , 1cid , 1ciu , 1cl7 , 1clc , 1clo , 1clz , 1cqy , 1cs6 , 1ctn , 1cvr , 1cvs , 1cxe , 1cxf , 1cxh , 1cxi , 1cxk , 1cxl , 1cyg , 1d3c , 1d3l , 1d5b , 1d5i , 1d5m , 1d5x , 1d5z , 1d6e , 1d6v , 1d7f , 1d9k , 1dba , 1dbb , 1dbj , 1dbk , 1dbm , 1dcl , 1ddh , 1de4 , 1ded , 1djs , 1dlh , 1dn0 , 1dn2 , 1dqm , 1dqq , 1dqt , 1dr9 , 1dtu , 1duy , 1duz , 1dvf , 1e0o , 1e27 , 1e28 , 1e4j , 1e4k , 1e6j , 1ea9 , 1eaj , 1ed3 , 1edq , 1eeq , 1eeu , 1eey , 1eez , 1efq , 1efx , 1egj , 1eh9 , 1eha , 1ehn , 1eib , 1ejo , 1ek3 , 1eo5 , 1eo7 , 1epf , 1es0 , 1eur , 1eus , 1eut , 1euu , 1ev2 , 1evt , 1evu , 1ex0 , 1exu , 1ezv , 1f11 , 1f13 , 1f2q , 1f3j , 1f42 , 1f45 , 1f58 , 1f5w , 1f6a , 1f6l , 1f97 , 1fai , 1fbi , 1fc1 , 1fcc , 1fcg , 1ffn , 1ffo , 1ffp , 1ffq , 1ffr , 1fg2 , 1fhg , 1fie , 1flr , 1flt , 1fne , 1fng , 1fnl , 1fo0 , 1fp5 , 1fpt , 1fq9 , 1frt , 1fsk , 1fv1 , 1fyt , 1fzj , 1fzk , 1fzm , 1fzo , 1g0d , 1g0x , 1g0y , 1g1c , 1g1y , 1g6r , 1g7h , 1g7i , 1g7j , 1g7l , 1g7m , 1g7p , 1g7q , 1g84 , 1g9m , 1g9n , 1gaf , 1gc1 , 1ggb , 1ggc , 1ggi , 1ggt , 1ggu , 1ggy , 1gji , 1gl4 , 1gof , 1gog , 1goh , 1gpo , 1gsm , 1gvi , 1gxe , 1gya , 1gzp , 1gzq , 1h15 , 1h3g , 1h3p , 1h9v , 1hcf , 1hdm , 1he7 , 1hez , 1hh6 , 1hh9 , 1hhg , 1hhh , 1hhi , 1hhj , 1hhk , 1hi6 , 1hk6 , 1hkf , 1hkl , 1hla , 1hnf , 1hng , 1hoc , 1hqr , 1hsa , 1hsb , 1hxm , 1hxy , 1hyr , 1i1a , 1i1c , 1i1f , 1i1r , 1i1y , 1i3r , 1i4f , 1i75 , 1i7r , 1i7t , 1i7u , 1i7z , 1i85 , 1i8l , 1i8m , 1i9e , 1iak , 1iam , 1ic1 , 1ic4 , 1ic5 , 1ic7 , 1ie5 , 1iea , 1ieb , 1igc , 1igy , 1ii4 , 1iil , 1ij9 , 1ikn , 1im3 , 1im9 , 1imh , 1inq , 1ira , 1itb , 1itc , 1izj , 1izk , 1j05 , 1j0h , 1j0i , 1j0j , 1j0k , 1j0y , 1j0z , 1j10 , 1j11 , 1j12 , 1j18 , 1j1o , 1j1p , 1j1x , 1j86 , 1j87 , 1j88 , 1j89 , 1j8h , 1jbj , 1je6 , 1jf1 , 1jf5 , 1jf6 , 1jfq , 1jgd , 1jge , 1jgl , 1jgu , 1jgv , 1jhk , 1jht , 1ji1 , 1ji2 , 1jib , 1jk8 , 1jl4 , 1jl8 , 1jn6 , 1jnh , 1jnj , 1jnl , 1jnn , 1jpf , 1jpg , 1juf , 1jvk , 1jwm , 1jws , 1jwu , 1k2d , 1k3i , 1k3z , 1k5n , 1k8d , 1k8i , 1k9t , 1kac , 1kb5 , 1kbg , 1kc5 , 1kck , 1kcl , 1kcr , 1kcs , 1kcu , 1kcv , 1kel , 1kem , 1ken , 1kg0 , 1kgc , 1kj2 , 1kj3 , 1kjm , 1kjv , 1klg , 1klu , 1koa , 1kpr , 1ksr , 1kt2 , 1ktd , 1ktk , 1ktl , 1ktr , 1kul , 1kum , 1kv3 , 1l6x , 1l6z , 1l7i , 1l7t , 1l9m , 1l9n , 1ld9 , 1ldp , 1lds , 1le5 , 1le9 , 1leg , 1lei , 1lek , 1lil , 1lk2 , 1lnu , 1lo0 , 1lo2 , 1lo3 , 1lo4 , 1lo5 , 1lp9 , 1lve , 1m05 , 1m4k , 1m6o , 1m7x , 1maj , 1mak , 1mam , 1mcp , 1mhc , 1mhe , 1mi5 , 1mim , 1mlb , 1mnu , 1moe , 1mpa , 1mq8 , 1mqk , 1muj , 1mvu , 1mwa , 1my5 , 1my7 , 1n3n , 1n4x , 1n59 , 1n5a , 1nam , 1nan , 1nbq , 1nbv , 1nby , 1nbz , 1nca , 1ncb , 1ncc , 1ncd , 1ncn , 1nct , 1ncu , 1nd0 , 1ndg , 1ndm , 1neu , 1nez , 1nfa , 1nfd , 1nfi , 1nfk , 1ngp , 1ngq , 1nh6 , 1nko , 1nkr , 1npu , 1nqb , 1nud , 1nuf , 1nug , 1nun , 1o0v , 1o7s , 1o7v , 1od7 , 1od9 , 1oda , 1of2 , 1oga , 1ogt , 1ohq , 1oll , 1olz , 1onq , 1ooa , 1opg , 1oqx , 1orq , 1ors , 1osp , 1osz , 1ot1 , 1ot2 , 1ovz , 1ow0 , 1owr , 1oy3 , 1p4b , 1p4i , 1p4l , 1p53 , 1p69 , 1p6a , 1p6f , 1p7h , 1p7k , 1p7q , 1p9m , 1pam , 1pd6 , 1pew , 1pez , 1pj9 , 1pko , 1pkq , 1plg , 1pqz , 1psk , 1pvh , 1pw3 , 1py4 , 1py9 , 1pzu , 1q0x , 1q0y , 1q8m , 1q94 , 1qbl , 1qd0 , 1qew , 1qfh , 1qfo , 1qfp , 1qho , 1qhp , 1qlf , 1qlr , 1qnz , 1qo3 , 1qok , 1qp1 , 1qqd , 1qr1 , 1qrk , 1qrn , 1qse , 1qsf , 1qsv , 1qsz , 1qty , 1qvo , 1qz1 , 1r3h , 1r5v , 1r5w , 1ram , 1rd6 , 1rei , 1rhf , 1rih , 1rjy , 1rjz , 1rk0 , 1rk1 , 1rle , 1rpq , 1rq5 , 1rsf , 1ru9 , 1rua , 1ruk , 1rul , 1rum , 1rup , 1ruq , 1rur , 1rv6 , 1rvf , 1ry7 , 1rzj , 1rzk , 1s7q , 1s7r , 1s7s , 1s7t , 1s7u , 1s7v , 1s7w , 1s7x , 1s8d , 1s9k , 1s9v , 1s9w , 1s9x , 1s9y , 1sbb , 1seb , 1seq , 1sgx , 1sje , 1sjh , 1sma , 1smo , 1sq2 , 1svc , 1svz , 1sy6 , 1sys , 1syv , 1t0m , 1t0n , 1t0p , 1t1w , 1t1x , 1t1y , 1t1z , 1t20 , 1t21 , 1t22 , 1t2j , 1t2q , 1t2x , 1t5w , 1t5x , 1t66 , 1t6v , 1t6w , 1t7v , 1t7w , 1t7x , 1t7y , 1t7z , 1t80 , 1t83 , 1t89 , 1tcm , 1tcr , 1tit , 1tiu , 1tlk , 1tmc , 1tnm , 1tnn , 1ttu , 1tvb , 1tvh , 1u2c , 1u36 , 1u3h , 1u3j , 1u3y , 1u3z , 1u41 , 1u42 , 1u58 , 1u6a , 1u9k , 1uad , 1ub5 , 1ub6 , 1ucb , 1uct , 1ufu , 1ugn , 1uh2 , 1uh3 , 1uh4 , 1ukq , 1uks , 1ukt , 1um4 , 1um5 , 1um6 , 1uqs , 1url , 1ut9 , 1uxs , 1uxw , 1v05 , 1v3j , 1v3k , 1v3l , 1v3m , 1vac , 1vad , 1vb9 , 1vca , 1vdg , 1vem , 1ven , 1veo , 1vep , 1ver , 1ves , 1vfk , 1vfm , 1vfo , 1vfu , 1vgk , 1vjj , 1vkx , 1vsc , 1w0v , 1w0w , 1w72 , 1w8n , 1w8o , 1waa , 1wbx , 1wby , 1wbz , 1wcq , 1wf5 , 1wfn , 1wfo , 1wio , 1wip , 1wiq , 1wis , 1wit , 1wiu , 1wlh , 1wtl , 1wvz , 1wwa , 1wwb , 1wwc , 1www , 1wzk , 1wzl , 1wzm , 1x44 , 1x5y , 1x6l , 1x6n , 1x7q , 1xau , 1xed , 1xgy , 1xh3 , 1xiw , 1xmw , 1xr8 , 1xr9 , 1xz0 , 1ydp , 1yec , 1yed , 1yee , 1yef , 1yeg , 1yeh , 1yjd , 1ymm , 1yn6 , 1yn7 , 1ynk , 1ynl , 1ypz , 1z5l , 1za6 , 1zag , 1zan , 1zea , 1zgl , 1zhb , 1zhk , 1zhl , 1zhn , 1zs8 , 1zsd , 1zt1 , 1zt4 , 1zt7 , 1zvs , 1zxq , 25c8 , 2a1w , 2a6k , 2a83 , 2aav , 2adf , 2agj , 2ai0 , 2ajs , 2aju , 2ajx , 2ajy , 2ajz , 2ak1 , 2ak4 , 2akr , 2aq1 , 2aq2 , 2aq3 , 2arj , 2as5 , 2atp , 2av1 , 2av7 , 2avg , 2aw2 , 2axf , 2axg , 2axh , 2b4c , 2bck , 2ber , 2bhu , 2bhy , 2bhz , 2bnq , 2bnr , 2bnu , 2bp3 , 2brq , 2bsr , 2bss , 2bst , 2bve , 2bvo , 2bvp , 2bvq , 2bx5 , 2bxy , 2bxz , 2by0 , 2by1 , 2by2 , 2by3 , 2bzd , 2c5d , 2c7u , 2c9a , 2cd0 , 2cii , 2cik , 2cju , 2ckb , 2clr , 2clv , 2clz , 2cry , 2cxg , 2d0f , 2d0g , 2d0h , 2d2o , 2d31 , 2d4d , 2d4f , 2d7m , 2d7n , 2d7o , 2d7p , 2d7q , 2dav , 2dbl , 2df3 , 2di8 , 2di9 , 2dia , 2dib , 2dic , 2dij , 2dj4 , 2dl2 , 2dlf , 2dlg , 2dli , 2dmb , 2dmc , 2dqc , 2dqd , 2dqe , 2dqf , 2dtq , 2dts , 2dyp , 2e7l , 2e9i , 2eed , 2eib , 2eic , 2eid , 2eie , 2esv , 2f19 , 2f53 , 2f54 , 2f74 , 2f8o , 2fb4 , 2fbj , 2fcb , 2fd6 , 2fdb , 2fhb , 2fhc , 2fhf , 2fik , 2fl5 , 2fo1 , 2fo4 , 2fse , 2fwo , 2fyy , 2fz3 , 2g5r , 2g9h , 2gaz , 2gi7 , 2git , 2gj6 , 2gj7 , 2gsi , 2gt9 , 2gtw , 2gtz , 2guo , 2h26 , 2h32 , 2h3n , 2h6p , 2hjk , 2hjl , 2hla , 2hlf , 2hn7 , 2hp4 , 2hrl , 2ht2 , 2ht3 , 2ht4 , 2htk , 2htl , 2i26 , 2i27 , 2i9t , 2iad , 2ial , 2iam , 2ian , 2ibz , 2icw , 2ifg , 2ig2 , 2ij0 , 2ipk , 2iwg , 2j12 , 2j1k , 2j3s , 2j4w , 2j6e , 2j8u , 2jcc , 2jf1 , 2jkx , 2lve , 2mcg , 2mcp , 2mha , 2mpa , 2ncm , 2nna , 2nqc , 2nts , 2nw2 , 2nw3 , 2nx5 , 2nxy , 2nxz , 2ny0 , 2ny1 , 2ny2 , 2ny3 , 2ny4 , 2ny5 , 2ny6 , 2o61 , 2o93 , 2oi9 , 2oje , 2ojz , 2ok0 , 2ol3 , 2om5 , 2oz4 , 2p24 , 2p49 , 2p4a , 2p5e , 2p5w , 2po6 , 2pxy , 2pye , 2q3z , 2q6w , 2q7y , 2q86 , 2qad , 2qej , 2ql1 , 2ram , 2rcs , 2rfx , 2seb , 2uwe , 2v2t , 2v2w , 2v2x , 2vaa , 2vab , 2vb5 , 2ve6 , 2vir , 2vis , 2vlj , 2vlk , 2vll , 2vlr , 2vol , 2vz1 , 2vz3 , 2w0p , 2yxf , 2z31 , 2z35 , 2z9t , 2zok , 2zol , 3b3i , 3b5h , 3b6s , 3bev , 3bew , 3bgm , 3bh8 , 3bh9 , 3bhb , 3bik , 3bj9 , 3bmv , 3bmw , 3bn9 , 3bp5 , 3brd , 3brf , 3brg , 3buy , 3bw9 , 3bwa , 3bze , 3bzf , 3c5z , 3c60 , 3c6l , 3c8k , 3c9n , 3cd4 , 3cdg , 3cgt , 3cii , 3cmo , 3d2u , 3d85 , 3d87 , 3dar , 3dj9 , 3duh , 3dvg , 3dvn , 3fru , 3hla , 3lve , 3ncm , 43c9 , 4cgt , 4fab , 4lve , 5bca , 5cgt , 5lve , 6cgt , 6fab , 7cgt , 7fab , 8cgt , 9cgt

Taxonomic coverageHelp
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Overlapping InterPro entriesHelp
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IPR013783 Numbers of overlapping proteins Average numbers of overlapping amino acids

Example proteinsHelp
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O00241 Signal-regulatory protein beta-1

O01761 Muscle M-line assembly protein unc-89

O08665 Semaphorin-3A

P20241 Neuroglian

P32775 1,4-alpha-glucan-branching enzyme

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR013781 Glycoside hydrolase, subgroup, catalytic core
IPR013780 Glycosyl hydrolase, family 13, all-beta
IPR013783 Immunoglobulin-like fold
IPR006047 Glycosyl hydrolase, family 13, catalytic domain
IPR006048 Alpha-amylase, C-terminal all beta
IPR017442 Serine/threonine-protein kinase-like domain
IPR014756 Immunoglobulin E-set
IPR013098 Immunoglobulin I-set
IPR007850 RCSD
IPR016201 Plexin-like fold
IPR011009 Protein kinase-like domain
IPR008957 Fibronectin, type III-like fold
IPR013106 Immunoglobulin V-set
IPR000719 Protein kinase, catalytic domain
IPR017853 Glycoside hydrolase, catalytic core
IPR003961 Fibronectin, type III
IPR015943 WD40/YVTN repeat-like-containing domain
IPR011993 Pleckstrin homology-type
IPR007110 Immunoglobulin-like
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR003597 Immunoglobulin C1-set
IPR001849 Pleckstrin homology
IPR000219 Dbl homology (DH) domain
IPR001452 Src homology-3 domain
IPR013151 Immunoglobulin
IPR004193 Glycoside hydrolase, family 13, N-terminal
IPR001627 Semaphorin/CD100 antigen
IPR003659 Plexin/semaphorin/integrin
IPR009134 Tyrosine-protein kinase, vascular endothelial growth factor receptor (VEGFR), N-terminal
ModBase
SWISS-MODEL
PDB Chain
CATH Domain
SCOP Domain

PublicationsHelp
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1. Bork P, Holm L, Sander C.
The immunoglobulin fold. Structural classification, sequence patterns and common core.
J. Mol. Biol. 242 309-20 1994 [PubMed: 7932691]
2. Halaby DM, Poupon A, Mornon J.
The immunoglobulin fold family: sequence analysis and 3D structure comparisons.
Protein Eng. 12 563-71 1999 [PubMed: 10436082]
http://dx.doi.org/10.1093/protein/12.7.563
3. Potapov V, Sobolev V, Edelman M, Kister A, Gelfand I.
Protein--protein recognition: juxtaposition of domain and interface cores in immunoglobulins and other sandwich-like proteins.
J. Mol. Biol. 342 665-79 2004 [PubMed: 15327963]
http://dx.doi.org/10.1016/j.jmb.2004.06.072
4. Teichmann SA, Chothia C.
Immunoglobulin superfamily proteins in Caenorhabditis elegans.
J. Mol. Biol. 296 1367-83 2000 [PubMed: 10698639]
http://dx.doi.org/10.1006/jmbi.1999.3497
5. Bodian DL, Jones EY, Harlos K, Stuart DI, Davis SJ.
Crystal structure of the extracellular region of the human cell adhesion molecule CD2 at 2.5 A resolution.
Structure 2 755-66 1994 [PubMed: 7994575]
http://dx.doi.org/10.1016/S0969-2126(94)00076-X

Additional ReadingHelp
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Takala H, Nurminen E, Nurmi SM, Aatonen M, Strandin T, Takatalo M, Kiema T, Gahmberg CG, Ylanne J, Fagerholm SC.
Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding.
Blood 112 2008 1853-62 [PubMed: 18550856]
http://dx.doi.org/10.1182/blood-2007-12-127795
Covaceuszach S, Cassetta A, Konarev PV, Gonfloni S, Rudolph R, Svergun DI, Lamba D, Cattaneo A.
Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody.
J. Mol. Biol. 381 2008 881-96 [PubMed: 18635195]
http://dx.doi.org/10.1016/j.jmb.2008.06.008
Ababou A, Rostkova E, Mistry S, Le Masurier C, Gautel M, Pfuhl M.
Myosin binding protein C positioned to play a key role in regulation of muscle contraction: structure and interactions of domain C1.
J. Mol. Biol. 384 2008 615-30 [PubMed: 18926831]
http://dx.doi.org/10.1016/j.jmb.2008.09.065
Bates DL, Barthel KK, Wu Y, Kalhor R, Stroud JC, Giffin MJ, Chen L.
Crystal structure of NFAT bound to the HIV-1 LTR tandem kappaB enhancer element.
Structure 16 2008 684-94 [PubMed: 18462673]
http://dx.doi.org/10.1016/j.str.2008.01.020
McBeth C, Seamons A, Pizarro JC, Fleishman SJ, Baker D, Kortemme T, Goverman JM, Strong RK.
A new twist in TCR diversity revealed by a forbidden alphabeta TCR.
J. Mol. Biol. 375 2008 1306-19 [PubMed: 18155234]
http://dx.doi.org/10.1016/j.jmb.2007.11.020
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