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InterPro: IPR013678 Ribonucleotide reductase class II vitamin B12-dependent

Protein matches Help

UniProtKB

Matches:

191 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR013678 Ribonuc_red_2_N

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF08471	Ribonuc_red_2_N	191
Signatures in BioMart

GO Term annotation Help

Process

GO:0055114 oxidation reduction

Function

GO:0004748 ribonucleoside-diphosphate reductase activity
GO:0050897 cobalt ion binding

InterPro annotation

Entry Details in BioMart

Abstract

This domain is found to the N terminus of the ribonucleotide reductase barrel domain (IPR000788). It occurs in bacterial class II ribonucleotide reductase proteins which depend upon coenzyme B12 (deoxyadenosylcobalamine) [1].

Database links Help

Enzyme: EC:1.17.4.1

Taxonomic coverage Help

Example proteins Help

O54196 Vitamin B12-dependent ribonucleotide reductase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR000788	Ribonucleotide reductase large subunit, C-terminal
IPR013678	Ribonucleotide reductase class II vitamin B12-dependent
IPR013344	Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent
	SWISS-MODEL
	ModBase

Publications Open in usermanual
1.	Borovok I, Kreisberg-Zakarin R, Yanko M, Schreiber R, Myslovati M, Aslund F, Holmgren A, Cohen G, Aharonowitz Y. Streptomyces spp. contain class Ia and class II ribonucleotide reductases: expression analysis of the genes in vegetative growth. Microbiology (Reading, Engl.) 148 391-404 2002 [PubMed: 11832503] http://mic.sgmjournals.org/cgi/content/abstract/148/2/391

InterPro 23.1