This family consists of examples of mannosyl-3-phosphoglycerate synthase (MPGS), which together with mannosyl-3-phosphoglycerate phosphatase (MPGP), comprises a two-step pathway for mannosylglycerate biosynthesis. Mannosylglycerate is a compatible solute that tends to be restricted to extreme thermophiles of archaea and bacteria. Note that in Rhodothermus marinus (Rhodothermus obamensis), this pathway is one of two; the other is condensation of GDP-mannose with D-glycerate by mannosylglycerate synthase.
Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS.
The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate.
Appl. Environ. Microbiol. 69 2003 3272-9
[PubMed: 12788726] http://dx.doi.org/10.1128/AEM.69.6.3272-3279.2003
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