EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR012768 Malto-oligosyltrehalose trehalohydrolase

Protein matches Help

UniProtKB

Matches:

349 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR012768 Trehalose_TreZ

Type

Family

Signatures Help

Database	ID	Name	Proteins
PIRSF	PIRSF006337	Trehalose_TreZ	338
TIGRFAMs	TIGR02402	trehalose_TreZ	342
Signatures in BioMart

InterPro Relationships Help

Contains

IPR004193 Glycoside hydrolase, family 13, N-terminal
IPR006047 Glycosyl hydrolase, family 13, catalytic domain
IPR013783 Immunoglobulin-like fold
IPR014756 Immunoglobulin E-set
IPR015156 Malto-oligosyltrehalose trehalohydrolase, C-terminal

GO Term annotation Help

Process

GO:0005992 trehalose biosynthetic process

Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

InterPro annotation

Entry Details in BioMart

Abstract

Members of this family are the trehalose biosynthetic enzyme malto-oligosyltrehalose trehalohydrolase, formally known as 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC:3.2.1.141). It is the TreZ protein of the TreYZ pathway for trehalose biosynthesis, and alternative to the OtsAB system.

Structural links Help

PDB - click here

SCOP: b.1.18.2 , b.71.1.1 , c.1.8.1

CATH: 2.60.40.10 , 2.60.40.1180 , 3.20.20.80

Database links Help

Enzyme: EC:3.2.1.141

CluSTr: ALLvsALL:36403:116

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR012768

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O52520 Malto-oligosyltrehalose trehalohydrolase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013781	Glycoside hydrolase, subgroup, catalytic core
IPR012768	Malto-oligosyltrehalose trehalohydrolase
IPR013783	Immunoglobulin-like fold
IPR006047	Glycosyl hydrolase, family 13, catalytic domain
IPR017853	Glycoside hydrolase, catalytic core
IPR014756	Immunoglobulin E-set
	ModBase

Publications Help

Additional Reading Open in usermanual
	Leiros HK, Timmins J, Ravelli RB, McSweeney SM. Is radiation damage dependent on the dose rate used during macromolecular crystallography data collection? Acta Crystallogr. D Biol. Crystallogr. 62 2006 125-32 [PubMed: 16421442] http://dx.doi.org/10.1107/S0907444905033627
	Timmins J, Leiros HK, Leonard G, Leiros I, McSweeney S. Crystal structure of maltooligosyltrehalose trehalohydrolase from Deinococcus radiodurans in complex with disaccharides. J. Mol. Biol. 347 2005 949-63 [PubMed: 15784255] http://dx.doi.org/10.1016/j.jmb.2005.02.011
	Feese MD, Kato Y, Tamada T, Kato M, Komeda T, Miura Y, Hirose M, Hondo K, Kobayashi K, Kuroki R. Crystal structure of glycosyltrehalose trehalohydrolase from the hyperthermophilic archaeum Sulfolobus solfataricus. J. Mol. Biol. 301 2000 451-64 [PubMed: 10926520] http://dx.doi.org/10.1006/jmbi.2000.3977

InterPro 23.1