EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR012480 Heparinase II/III-like

Protein matches Help

UniProtKB

Matches:

557 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR012480 Hepar_II_III

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF07940	Hepar_II_III	557
Signatures in BioMart

InterPro annotation

Entry Details in BioMart

Abstract

This family features sequences that are similar to a region of the Flavobacterium heparinum proteins heparinase II (Q46080) and heparinase III (Q59289). The former is known to degrade heparin and heparan sulphate, whereas the latter predominantly degrades heparan sulphate. Both are secreted into the periplasmic space upon induction with heparin [1].

Database links Help

PANDIT: PF07940

Blocks: IPB012480

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR012480

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

Q46080 Heparinase II protein

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR012480	Heparinase II/III-like
	PDB Chain

Publications Help

Su H, Blain F, Musil RA, Zimmermann JJ, Gu K, Bennett DC.
Isolation and expression in Escherichia coli of hepB and hepC, genes coding for the glycosaminoglycan-degrading enzymes heparinase II and heparinase III, respectively, from Flavobacterium heparinum.
Appl. Environ. Microbiol. 62 2723-34 1996 [PubMed: 8702264]
http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=8702264&action=stream&blobtype=pdf

InterPro 23.1