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InterPro: IPR012142 Tryptophan 2-monooxygenase

Protein matches Help

UniProtKB

Matches:

16 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR012142 Trp_2-mOase

Type

Family

Signatures Help

Database	ID	Name	Proteins
PIRSF	PIRSF000319	Trp_2-mono_O2ase	16
Signatures in BioMart

InterPro Relationships Help

Contains

IPR000759 Adrenodoxin reductase
IPR002937 Amine oxidase
IPR006064 Cytokinin glycosidase

GO Term annotation Help

Process

GO:0009851 auxin biosynthetic process
GO:0055114 oxidation reduction

Function

GO:0050361 tryptophan 2-monooxygenase activity

InterPro annotation

Entry Details in BioMart

Abstract

The FAD-containing tryptophan 2-monooxygenase enzyme catalyses the oxidation of tryptophan to indoleacetamide, carbon dioxide, and water [1].The enzyme belongs to a group of flavoenzymes that catalyse the oxidative decarboxylation of amino acids.

Database links Help

Enzyme: EC:1.13.12.3

CluSTr: ALLvsALL:723043:205.9

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR012142

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P0A3V2 Tryptophan 2-monooxygenase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR006064	Cytokinin glycosidase
IPR012142	Tryptophan 2-monooxygenase
IPR002937	Amine oxidase
IPR000759	Adrenodoxin reductase
	ModBase

Publications Open in usermanual
1.	Sobrado P, Fitzpatrick PF. Identification of Tyr413 as an active site residue in the flavoprotein tryptophan 2-monooxygenase and analysis of its contribution to catalysis. Biochemistry 42 13833-8 2003 [PubMed: 14636050] http://dx.doi.org/10.1021/bi035300i

InterPro 23.1