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InterPro: IPR011835 Glycogen/starch synthases, ADP-glucose type

Protein matches Help

UniProtKB

Matches:

1343 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR011835 GlgA

Type

Domain

Signatures Help

Database	ID	Name	Proteins
HAMAP	MF_00484	GlgA	1113
TIGRFAMs	TIGR02095	glgA	1342
Signatures in BioMart

InterPro Relationships Help

Contains

IPR001296 Glycosyl transferase, group 1
IPR013534 Starch synthase, catalytic domain

GO Term annotation Help

Process

GO:0009250 glucan biosynthetic process

Function

GO:0009011 starch synthase activity

InterPro annotation

Entry Details in BioMart

Abstract

This family consists of glycogen (or starch) synthases that use ADP-glucose (EC:2.4.1.21), rather than UDP-glucose (EC:2.4.1.11) as in animals, as the glucose donor. This enzyme is found in bacteria and plants. Whether the name given is glycogen synthase or starch synthase depends on context, and therefore on substrate.

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1)

Structural links Help

PDB - click here

SCOP: c.87.1.8

Database links Help

Enzyme: EC:2.4.1.21

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR011835

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

A2Y8X2 Granule-bound starch synthase 1, chloroplastic/amyloplastic

P0A3F3 Glycogen synthase 1

P72623 Probable glycogen synthase 2

Q59001 Probable glycogen synthase

Q9FNF2 Soluble starch synthase, chloroplastic/amyloplastic

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013534	Starch synthase, catalytic domain
IPR011835	Glycogen/starch synthases, ADP-glucose type
IPR001296	Glycosyl transferase, group 1
	SWISS-MODEL
	PDB Chain
	ModBase
	SCOP Domain

Publications Help

Additional Reading Open in usermanual
	Buschiazzo A, Ugalde JE, Guerin ME, Shepard W, Ugalde RA, Alzari PM. Crystal structure of glycogen synthase: homologous enzymes catalyze glycogen synthesis and degradation. EMBO J. 23 2004 3196-205 [PubMed: 15272305] http://dx.doi.org/10.1038/sj.emboj.7600324
	Horcajada C, Guinovart JJ, Fita I, Ferrer JC. Crystal structure of an archaeal glycogen synthase: insights into oligomerization and substrate binding of eukaryotic glycogen synthases. J. Biol. Chem. 281 2006 2923-31 [PubMed: 16319074] http://dx.doi.org/10.1074/jbc.M507394200

InterPro 23.1