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InterPro: IPR011717 Tetratricopeptide TPR-4

Protein matches Help

UniProtKB

Matches:

2113 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR011717 TPR-4

Type

Repeat

Signatures Help

Database	ID	Name	Proteins
Pfam	PF07721	TPR_4	2113
Signatures in BioMart

InterPro Relationships Help

Found in

IPR003921 Cellulose synthase, subunit C
IPR011990 Tetratricopeptide-like helical
IPR013026 Tetratricopeptide repeat-containing domain
IPR014266 PEP-CTERM system TPR-repeat lipoprotein, putative
IPR014596 Uncharacterised conserved protein UCP035836
IPR016236 Serine/threonine-protein kinase PknK, predicted

InterPro annotation

Entry Details in BioMart

Abstract

This entry includes tetratricopeptide-like repeats not detected by the IPR001440, IPR013105 and IPR011716 models. The tetratricopeptide repeat (TPR) motif is a protein-protein interaction module found in multiple copies in a number of functionally different proteins that facilitates specific interactions with a partner protein(s) [1].

Database links Help

PANDIT: PF07721

Blocks: IPB011717

Pfam Clan: CL0020.21

Interactions Help

This domain has been experimentally proven to be involved in Protein:Protein interactions.
Representative data is shown with the following example proteins:

Taxonomic coverage Help

Example proteins Help

A2A3L6 Tetratricopeptide repeat protein 24

O82861 Cellulose synthase operon protein C

Q0HA38 Tetratricopeptide repeat protein 21B

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR011990	Tetratricopeptide-like helical
IPR003921	Cellulose synthase, subunit C
IPR013026	Tetratricopeptide repeat-containing domain
IPR013105	Tetratricopeptide TPR2
IPR001440	Tetratricopeptide TPR-1
IPR019734	Tetratricopeptide repeat
IPR008410	Cellulose synthase operon C, C-terminal
IPR011717	Tetratricopeptide TPR-4
	SWISS-MODEL
	ModBase

Publications Open in usermanual
1.	Blatch GL, Lassle M. The tetratricopeptide repeat: a structural motif mediating protein-protein interactions. Bioessays 21 932-9 1999 [PubMed: 10517866] http://dx.doi.org/10.1002/(SICI)1521-1878(199911)21:11<932::AID-BIES5>3.3.CO;2-E

Additional Reading Open in usermanual
	Du Q, Macara IG. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell 119 2004 503-16 [PubMed: 15537540] http://dx.doi.org/10.1016/j.cell.2004.10.028

InterPro 23.1