EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR010502 Carbohydrate-binding domain, family 9

Protein matches Help

UniProtKB

Matches:

91 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR010502 Carb-bd_dom_fam9

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF06452	DUF1083	91
Signatures in BioMart

InterPro Relationships Help

Parent

IPR015922 Carbohydrate-binding domain, family 9-like, subgroup

GO Term annotation Help

Process

GO:0016052 carbohydrate catabolic process

Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0030246 carbohydrate binding

InterPro annotation

Entry Details in BioMart

Abstract

This entry represents the family 9 carbohydrate-binding module (CBD9), which exhibit an immunoglobulin-like beta-sandwich fold, with an additional beta-strand at the N terminus [1].

Bacterial extracellular cellulases and hemicellulases are involved in the hydrolysis of the major structural polysaccharides of plant cell walls. These are usually modular enzymes that contain catalytic and non-catalytic domains. The CBD9 domain binds to cellulose, xylan, as well as to a range of soluble di- and mono-saccharides, and is found in cellulose- and xylan-degrading enzymes, such as endo-1,4-beta-xylanase (EC:3.2.1.8) [2].

Structural links Help

PDB - click here

SCOP: b.1.9.2

CATH: 2.60.40.1190

Database links Help

Enzyme: EC:3.2.1.8

PANDIT: PF06452

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR010502

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

Q60037 Endo-1,4-beta-xylanase A

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR003305	Carbohydrate-binding, CenC-like
IPR013781	Glycoside hydrolase, subgroup, catalytic core
IPR015922	Carbohydrate-binding domain, family 9-like, subgroup
IPR010502	Carbohydrate-binding domain, family 9
IPR001000	Glycoside hydrolase, family 10
IPR008979	Galactose-binding domain-like
IPR017853	Glycoside hydrolase, catalytic core
IPR008960	Carbohydrate-binding domain family 9-like
	PDB Chain
	ModBase
	CATH Domain
	SWISS-MODEL
	SCOP Domain

Publications Open in usermanual
1.	Rotsaert FA, Hallberg BM, de Vries S, Moenne-Loccoz P, Divne C, Renganathan V, Gold MH. Biophysical and structural analysis of a novel heme B iron ligation in the flavocytochrome cellobiose dehydrogenase. J. Biol. Chem. 278 33224-31 2003 [PubMed: 12796496] http://dx.doi.org/10.1074/jbc.M302653200
2.	Hazlewood GP, Gilbert HJ. Structure and function analysis of Pseudomonas plant cell wall hydrolases. Prog. Nucleic Acid Res. Mol. Biol. 61 211-41 1998 [PubMed: 9752722]

Additional Reading Open in usermanual
	Notenboom V, Boraston AB, Kilburn DG, Rose DR. Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms. Biochemistry 40 2001 6248-56 [PubMed: 11371186] http://dx.doi.org/10.1021/bi0101704

InterPro 23.1