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InterPro: IPR010324 Dam-replacing

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UniProtKB
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45 proteins
AccessionHelp IPR010324 DRP
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AbstractHelp

Dam-replacing protein (DRP) is a restriction endonuclease that is flanked by pseudo-transposable small repeat elements. The replacement of Dam-methylase by DRP allows phase variation through slippage-like mechanisms in several pathogenic isolates of Neisseria meningitidis [1].

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PANDIT: PF06044

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Example proteinsHelp
P0A459 Type-2 restriction enzyme DpnI

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InterPro entry accession number/name and structure databases Colour code
IPR010324 Dam-replacing

PublicationsHelp
1. Cantalupo G, Bucci C, Salvatore P, Pagliarulo C, Roberti V, Lavitola A, Bruni CB, Alifano P.
Evolution and function of the neisserial dam-replacing gene.
FEBS Lett. 495 178-83 2001 [PubMed: 11334887]
http://dx.doi.org/10.1016/S0014-5793(01)02388-2

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InterPro 23.1