EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR010219 NADH dehydrogenase I, D subunit

Protein matches Help

UniProtKB

Matches:

1043 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR010219 NADH_DH_1_dsu

Type

Domain

Signatures Help

Database	ID	Name	Proteins
TIGRFAMs	TIGR01962	NuoD	1043
Signatures in BioMart

InterPro Relationships Help

Contains

IPR001135 NADH-quinone oxidoreductase, subunit D
IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site

GO Term annotation Help

Process

GO:0055114 oxidation reduction

Function

GO:0016651 oxidoreductase activity, acting on NADH or NADPH

InterPro annotation

Entry Details in BioMart

Abstract

This entry recognises specifically the D subunit of NADH dehydrogenase I complex. It excludes the related chain of NAD(P)H-quinone oxidoreductases from chloroplast and Synechocystis, where the quinone may be plastoquinone rather than ubiquinone. This subunit often appears as a subunit C/D fusion.

Structural links Help

PDB - click here

SCOP: e.18.1.2

Database links Help

Enzyme: EC:1.6.99.5

CluSTr: ALLvsALL:30866:103.8

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR010219

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O75306 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

P93306 NADH-ubiquinone oxidoreductase 49 kDa subunit

Q56220 NADH-quinone oxidoreductase subunit 4

Q91WD5 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

Q93873 Probable NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR014029	NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site
IPR010219	NADH dehydrogenase I, D subunit
IPR001135	NADH-quinone oxidoreductase, subunit D
	SWISS-MODEL
	PDB Chain
	ModBase
	SCOP Domain

Publications Help

Additional Reading Open in usermanual
	Sazanov LA, Hinchliffe P. Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus. Science 311 2006 1430-6 [PubMed: 16469879] http://dx.doi.org/10.1126/science.1123809

InterPro 23.1