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InterPro: IPR009875 Type IV pilus assembly PilZ

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UniProtKB
Matches:
2486 proteins
AccessionHelp IPR009875 PilZ
TypeHelp Domain
SignaturesHelp
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Found in IPR017480 Cellulose synthase catalytic subunit (UDP-forming)
InterPro annotation
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AbstractHelp

This entry is found in several bacterial type IV pilus assembly (PilZ) proteins. PilZ is thought to have a cytoplasmic location and be essential for type 4 fimbrial biogenesis but its exact function is unknown [1].

Structural linksHelp
SCOP: b.45.2.1
CATH: 2.40.10.220
Database linksHelp
PANDIT: PF07238

Taxonomic coverageHelp

Overlapping InterPro entriesHelp
IPR009875 Numbers of overlapping proteins Average numbers of overlapping amino acids

Example proteinsHelp
O67264 Uncharacterized protein aq_1211

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Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR009875 Type IV pilus assembly PilZ
SWISS-MODEL

PublicationsHelp
1. Alm RA, Bodero AJ, Free PD, Mattick JS.
Identification of a novel gene, pilZ, essential for type 4 fimbrial biogenesis in Pseudomonas aeruginosa.
J. Bacteriol. 178 46-53 1996 [PubMed: 8550441]
http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=8550441

Additional ReadingHelp
Benach J, Swaminathan SS, Tamayo R, Handelman SK, Folta-Stogniew E, Ramos JE, Forouhar F, Neely H, Seetharaman J, Camilli A, Hunt JF.
The structural basis of cyclic diguanylate signal transduction by PilZ domains.
EMBO J. 26 2007 5153-66 [PubMed: 18034161]
http://dx.doi.org/10.1038/sj.emboj.7601918
Ramelot TA, Yee A, Cort JR, Semesi A, Arrowsmith CH, Kennedy MA.
NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein.
Proteins 66 2007 266-71 [PubMed: 17096419]
http://dx.doi.org/10.1002/prot.21199
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InterPro 23.1