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InterPro: IPR009031 Type X cellulose-binding domain, CBDX

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UniProtKB

Matches:

66 proteins

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Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
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Architectures
Accession List
Matches in BioMart

Accession

IPR009031 TypeX_cellulose-bd_dom_CBDX

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Gene3D	G3DSA:2.30.32.30	TypeX_cellulose-bd_reg_CBDX	61
SuperFamily	SSF57615	CBDX	66
Signatures in BioMart

InterPro Relationships Help

Parent

IPR002883 Dockerin cellulose-binding domain

GO Term annotation Help

Process

GO:0005975 carbohydrate metabolic process

Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

InterPro annotation

Entry Details in BioMart

Abstract

Plant cell wall hydrolases from aerobic microorganisms generally have a modular structure consisting of a catalytic domain linked to one or more carbohydrate-binding modules (CBMs). CBMs function to attach the enzyme to the polymeric substrate, thereby increasing the catalytic activity. Most CBMs bind cellulose and are referred to as cellulose-binding domains (CBDs), while some can also bind xylan (XBM). CBMs have been classified into families based on sequence similarities. For example, Xylanase A from Cellvibrio japonicus [1] contains a family 2a CBM followed by a family 10 CBM. The structure of the type X CBD (CBDX) consists of an alpha/beta fold that is disulphide-rich.

Structural links Help

PDB - click here

SCOP: g.29.1.1

CATH: 2.30.32.30

Database links Help

Enzyme: EC:3.2.1

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR009031

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P14768 Endo-1,4-beta-xylanase A

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013781	Glycoside hydrolase, subgroup, catalytic core
IPR012291	Cellulose-binding family II/chitobiase, carbohydrate-binding domain
IPR002883	Dockerin cellulose-binding domain
IPR008965	Carbohydrate-binding
IPR001000	Glycoside hydrolase, family 10
IPR017853	Glycoside hydrolase, catalytic core
IPR001919	Cellulose-binding domain, family II, bacterial type
IPR018366	Carbohydrate-binding type-2, conserved site
IPR009031	Type X cellulose-binding domain, CBDX
	PDB Chain
	ModBase
	CATH Domain
	SWISS-MODEL
	SCOP Domain

Publications Open in usermanual
1.	Raghothama S, Simpson PJ, Szabo L, Nagy T, Gilbert HJ, Williamson MP. Solution structure of the CBM10 cellulose binding module from Pseudomonas xylanase A. Biochemistry 39 978-84 2000 [PubMed: 10653641] http://dx.doi.org/10.1021/bi992163+

InterPro 23.1