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InterPro: IPR008670 Acyl-CoA reductase

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UniProtKB

Matches:

169 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR008670 LuxC

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF05893	LuxC	169
Signatures in BioMart

InterPro Relationships Help

Contains

IPR016161 Aldehyde/histidinol dehydrogenase

GO Term annotation Help

Process

GO:0008218 bioluminescence
GO:0055114 oxidation reduction

Function

GO:0019109 acyl-CoA reductase activity

InterPro annotation

Entry Details in BioMart

Abstract

This family consists of several bacterial Acyl-CoA reductase (LuxC) proteins. The channelling of fatty acids into the fatty aldehyde substrate for the bacterial bioluminescence reaction is catalysed by a fatty acid reductase multienzyme complex, which channels fatty acids through the thioesterase (LuxD), synthetase (LuxE) and reductase (LuxC) components [1].

Database links Help

Enzyme: EC:1.2.1.50

PANDIT: PF05893

Blocks: IPB008670

Pfam Clan: CL0099.9

Taxonomic coverage Help

Example proteins Help

P08639 Acyl-CoA reductase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR008670	Acyl-CoA reductase
IPR016161	Aldehyde/histidinol dehydrogenase
	ModBase

Publications Open in usermanual
1.	Lee CY, Meighen EA. Cysteine-286 as the site of acylation of the Lux-specific fatty acyl-CoA reductase. Biochim. Biophys. Acta 1338 215-22 1997 [PubMed: 9128139] http://dx.doi.org/10.1016/S0167-4838(96)00203-8

InterPro 23.1