This group of proteins contains members of the BZR1/LAT61 family of plant transcriptional repressors involved in controlling the response to Brassinosteroids (BRs). BRs are plant hormones that play essential roles in growth and development. BZR1 binds directly to DNA repressing the synthesis of genes involved in BR synthesis. Phosphorylation of BZR1 by BIN1 targets BZR1 to the 20S proteosome, while dephosphorylation leads to nuclear accumulation of BZR1 [1].
He JX, Gendron JM, Sun Y, Gampala SS, Gendron N, Sun CQ, Wang ZY.
BZR1 is a transcriptional repressor with dual roles in brassinosteroid homeostasis and growth responses.
Science 307 1634-8 2005
[PubMed: 15681342] http://dx.doi.org/10.1126/science.1107580
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