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InterPro: IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal

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UniProtKB

Matches:

286 proteins

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Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
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Accession List
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Accession

IPR007516 Co_F420_Hydgase/DH_bsu_N

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF04422	FrhB_FdhB_N	286
Signatures in BioMart

InterPro Relationships Help

Found in

IPR017679 Coenzyme F420 hydrogenase, subunit beta

InterPro annotation

Entry Details in BioMart

Abstract

Coenzyme F420 hydrogenase (EC:1.12.99.1) reduces the low-potential two-electron acceptor coenzyme F420. This entry contains the N termini of F420 hydrogenase and dehydrogenase beta subunits [1, 2]. The N terminus of Methanobacterium formicicum formate dehydrogenase beta chain (EC:1.2.1.2, P06130) is also represented in this entry [3]. This region is often found in association with the 4Fe-4S binding domain, fer4 (IPR001450), and the C terminus IPR007525.

Database links Help

PANDIT: PF04422

Blocks: IPB007516

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR007516

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P06130 Formate dehydrogenase subunit beta

P46015 Uncharacterized protein all1601

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR009051	Alpha-helical ferredoxin
IPR017900	4Fe-4S ferredoxin, iron-sulphur binding, conserved site
IPR017896	4Fe-4S ferredoxin, iron-sulpur binding domain
IPR007525	Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal
IPR007516	Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal
IPR012285	Fumarate reductase, C-terminal
IPR001450	4Fe-4S ferredoxin, iron-sulphur binding, subgroup
	SWISS-MODEL
	ModBase

Publications Open in usermanual
1.	Alex LA, Reeve JN, Orme-Johnson WH, Walsh CT. Cloning, sequence determination, and expression of the genes encoding the subunits of the nickel-containing 8-hydroxy-5-deazaflavin reducing hydrogenase from Methanobacterium thermoautotrophicum delta H. Biochemistry 29 7237-44 1990 [PubMed: 2207102] http://dx.doi.org/10.1021/bi00483a011
2.	Baumer S, Ide T, Jacobi C, Johann A, Gottschalk G, Deppenmeier U. The F420H2 dehydrogenase from Methanosarcina mazei is a Redox-driven proton pump closely related to NADH dehydrogenases. J. Biol. Chem. 275 17968-73 2000 [PubMed: 10751389] http://dx.doi.org/10.1074/jbc.M000650200
3.	Shuber AP, Orr EC, Recny MA, Schendel PF, May HD, Schauer NL, Ferry JG. Cloning, expression, and nucleotide sequence of the formate dehydrogenase genes from Methanobacterium formicicum. J. Biol. Chem. 261 12942-7 1986 [PubMed: 3531194] http://intl.jbc.org/cgi/content/abstract/261/28/12942

InterPro 23.1