This is a domain found in proteins that transfer activated sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. Proteins bearing this domain transfer UDP, ADP, GDP or CMP linked sugars. This region is flanked at the N terminus by a signal peptide and at the C terminus by a glycosyl transferase group 1 domain (IPR001296). The eukaryotic glycogen synthases may be distant members of this bacterial family [1].
Brabetz W, Muller-Loennies S, Brade H.
3-Deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase (WaaA) and kdo kinase (KdkA) of Haemophilus influenzae are both required to complement a waaA knockout mutation of Escherichia coli.
J. Biol. Chem. 275 34954-62 2000
[PubMed: 10952982] http://dx.doi.org/10.1074/jbc.M005204200