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InterPro: IPR007507 Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal

Protein matchesHelp
UniProtKB
Matches:
941 proteins
AccessionHelp IPR007507 Glycos_transf_N
TypeHelp Domain
SignaturesHelp
GO Term annotationHelp
Process GO:0005975 carbohydrate metabolic process
Function GO:0005529 sugar binding
GO:0016740 transferase activity
InterPro annotation
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AbstractHelp

This is a domain found in proteins that transfer activated sugars to a variety of substrates, including glycogen, fructose-6-phosphate and lipopolysaccharides. Proteins bearing this domain transfer UDP, ADP, GDP or CMP linked sugars. This region is flanked at the N terminus by a signal peptide and at the C terminus by a glycosyl transferase group 1 domain (IPR001296). The eukaryotic glycogen synthases may be distant members of this bacterial family [1].

Database linksHelp
Enzyme: EC:2.4
PANDIT: PF04413
Blocks: IPB007507

Taxonomic coverageHelp

Example proteinsHelp
P0AC75 3-deoxy-D-manno-octulosonic-acid transferase

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Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR007507 Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal
IPR001296 Glycosyl transferase, group 1
SWISS-MODEL
ModBase

PublicationsHelp
1. Brabetz W, Muller-Loennies S, Brade H.
3-Deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase (WaaA) and kdo kinase (KdkA) of Haemophilus influenzae are both required to complement a waaA knockout mutation of Escherichia coli.
J. Biol. Chem. 275 34954-62 2000 [PubMed: 10952982]
http://dx.doi.org/10.1074/jbc.M005204200

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InterPro 23.1