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InterPro: IPR007112 Expansin 45, endoglucanase-like

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UniProtKB

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1201 proteins

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Accession List
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Accession

IPR007112 Expan_endogl

Type

Domain

Signatures Help

Database	ID	Name	Proteins
PROSITE profile	PS50842	EXPANSIN_EG45	1201
Signatures in BioMart

InterPro Relationships Help

Parent

IPR005132 Rare lipoprotein A

Found in

IPR002963 Expansin
IPR005795 Major pollen allergen Lol pI
IPR007118 Expansin/Lol pI

Contains

IPR009009 Barwin-related endoglucanase

InterPro annotation

Entry Details in BioMart

Abstract

Eukaryotic protein kinases [1, 2, 3, 4] are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases.

This group of genes codes for 9-kb striated preferentially expressed gene (SPEG)alpha and the 11-kb SPEGbeta found in skeletal muscle and heart. SPEGbeta encodes a 355kDa protein that contains two serine/threonine kinase domains and is homologous to proteins of the myosin light chain kinase family. At least one kinase domain is active and capable of autophosphorylation [5].

Structural links Help

PDB - click here

SCOP: b.52.1.3

CATH: 2.40.40.10 , 2.60.40.760

Database links Help

PROSITE doc: PDOC50842

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR007112

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

A2Y5R6 Expansin-A4

O22874 Expansin-A8

P43213 Pollen allergen Phl p 1

P43317 Endoglucanase-5

Q54C78 Expansin-like protein 9

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR014734	Pollen allergen, N-terminal
IPR007112	Expansin 45, endoglucanase-like
IPR005795	Major pollen allergen Lol pI
IPR007118	Expansin/Lol pI
IPR002963	Expansin
IPR007117	Pollen allergen/expansin, C-terminal
IPR000254	Cellulose-binding domain, fungal
IPR000334	Glycoside hydrolase, family 45
IPR005132	Rare lipoprotein A
IPR009009	Barwin-related endoglucanase
	PDB Chain
	ModBase
	CATH Domain
	SWISS-MODEL
	SCOP Domain

Publications Open in usermanual
1.	Hanks SK, Hunter T. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9 576-96 1995 [PubMed: 7768349] http://www.fasebj.org/cgi/content/abstract/9/8/576
2.	Hunter T. Protein kinase classification. Meth. Enzymol. 200 3-37 1991 [PubMed: 1835513] http://dx.doi.org/10.1016/0076-6879(91)00125-G
3.	Hanks SK, Quinn AM. Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. Meth. Enzymol. 200 38-62 1991 [PubMed: 1956325] http://dx.doi.org/10.1016/0076-6879(91)00126-H
4.	Hanks SK, Quinn AM, Hunter T. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. Science 241 42-52 1988 [PubMed: 3291115] http://www.sciencemag.org/cgi/content/abstract/241/4861/42
5.	Hsieh CM, Fukumoto S, Layne MD, Maemura K, Charles H, Patel A, Perrella MA, Lee ME. Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1. J. Biol. Chem. 275 36966-73 2000 [PubMed: 10973969] http://dx.doi.org/10.1074/jbc.M006028200

Additional Reading Open in usermanual
	Yennawar NH, Li LC, Dudzinski DM, Tabuchi A, Cosgrove DJ. Crystal structure and activities of EXPB1 (Zea m 1), a beta-expansin and group-1 pollen allergen from maize. Proc. Natl. Acad. Sci. U.S.A. 103 2006 14664-71 [PubMed: 16984999] http://dx.doi.org/10.1073/pnas.0605979103
	Cosgrove DJ. Loosening of plant cell walls by expansins. Nature 407 2000 321-6 [PubMed: 11014181] http://dx.doi.org/10.1038/35030000
	Cosgrove DJ, Bedinger P, Durachko DM. Group I allergens of grass pollen as cell wall-loosening agents. Proc. Natl. Acad. Sci. U.S.A. 94 1997 6559-64 [PubMed: 9177257] http://dx.doi.org/10.1073/pnas.94.12.6559
	Yuan S, Wu Y, Cosgrove DJ. A fungal endoglucanase with plant cell wall extension activity. Plant Physiol. 127 2001 324-33 [PubMed: 11553760] http://dx.doi.org/10.1104/pp.127.1.324
	Cullen DJ, Cullen BL. Postanesthetic complications. Surg. Clin. North Am. 55 1975 987-98 [PubMed: 1101418]
	Lee Y, Choi D, Kende H. Expansins: ever-expanding numbers and functions. Curr. Opin. Plant Biol. 4 2001 527-32 [PubMed: 11641069] http://dx.doi.org/10.1016/S1369-5266(00)00211-9

InterPro 23.1