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InterPro: IPR006584 Cellulose binding, type IV

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UniProtKB

Matches:

321 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR006584 Cellulose_bd_IV

Type

Domain

Signatures Help

Database	ID	Name	Proteins
SMART	SM00606	CBD_IV	321
Signatures in BioMart

InterPro Relationships Help

Parent

IPR005084 Carbohydrate binding domain, family 6

GO Term annotation Help

Function

GO:0030246 carbohydrate binding

InterPro annotation

Entry Details in BioMart

Abstract

This entry represents a type IV cellulose binding domain. It is a sub-domain of the carbohydrate-binding module, family 6 (GH6).

Regarding the function, it shows endohydrolysis of 1,4-beta-d-xylosidic linkages in xylans [1].

Structural links Help

PDB - click here

SCOP: b.18.1.10

CATH: 2.60.120.260

Database links Help

Enzyme: EC:3.2.1

Blocks: IPB006584

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR006584

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P10478 Endo-1,4-beta-xylanase Z

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR016134	Cellulosome enzyme, dockerin type I
IPR013781	Glycoside hydrolase, subgroup, catalytic core
IPR006584	Cellulose binding, type IV
IPR000801	Putative esterase
IPR005084	Carbohydrate binding domain, family 6
IPR001000	Glycoside hydrolase, family 10
IPR018247	EF-Hand 1, calcium-binding site
IPR008979	Galactose-binding domain-like
IPR002105	Cellulosome enzyme, dockerin type I, calcium-binding motif
IPR017853	Glycoside hydrolase, catalytic core
IPR018242	Dockerin type 1
	PDB Chain
	ModBase
	CATH Domain
	SWISS-MODEL
	SCOP Domain

Publications Open in usermanual
1.	Gosalbes MJ, Perez-Gonzalez JA, Gonzalez R, Navarro A. Two beta-glycanase genes are clustered in Bacillus polymyxa: molecular cloning, expression, and sequence analysis of genes encoding a xylanase and an endo-beta-(1,3)-(1,4)-glucanase. J. Bacteriol. 173 7705-10 1991 [PubMed: 1938968] http://jb.asm.org/cgi/content/abstract/173/23/7705

Additional Reading Open in usermanual
	Lammerts van Bueren A, Boraston AB. Binding sub-site dissection of a carbohydrate-binding module reveals the contribution of entropy to oligosaccharide recognition at "non-primary" binding subsites. J. Mol. Biol. 340 2004 869-79 [PubMed: 15223327] http://dx.doi.org/10.1016/j.jmb.2004.05.038
	Boraston AB, Notenboom V, Warren RA, Kilburn DG, Rose DR, Davies G. Structure and ligand binding of carbohydrate-binding module CsCBM6-3 reveals similarities with fucose-specific lectins and "galactose-binding" domains. J. Mol. Biol. 327 2003 659-69 [PubMed: 12634060] http://dx.doi.org/10.1016/S0022-2836(03)00152-9
	Czjzek M, Bolam DN, Mosbah A, Allouch J, Fontes CM, Ferreira LM, Bornet O, Zamboni V, Darbon H, Smith NL, Black GW, Henrissat B, Gilbert HJ. The location of the ligand-binding site of carbohydrate-binding modules that have evolved from a common sequence is not conserved. J. Biol. Chem. 276 2001 48580-7 [PubMed: 11673472] http://intl.jbc.org/cgi/content/full/276/51/48580
	van Bueren AL, Morland C, Gilbert HJ, Boraston AB. Family 6 carbohydrate binding modules recognize the non-reducing end of beta-1,3-linked glucans by presenting a unique ligand binding surface. J. Biol. Chem. 280 2005 530-7 [PubMed: 15501830] http://intl.jbc.org/cgi/reprint/280/1/530.pdf
	Pires VM, Henshaw JL, Prates JA, Bolam DN, Ferreira LM, Fontes CM, Henrissat B, Planas A, Gilbert HJ, Czjzek M. The crystal structure of the family 6 carbohydrate binding module from Cellvibrio mixtus endoglucanase 5a in complex with oligosaccharides reveals two distinct binding sites with different ligand specificities. J. Biol. Chem. 279 2004 21560-8 [PubMed: 15010454] http://dx.doi.org/10.1074/jbc.M401599200

InterPro 23.1