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InterPro: IPR006475 Citrate lyase, beta subunit, bacteria

Protein matchesHelp
UniProtKB
Matches:
272 proteins
AccessionHelp IPR006475 Citrate_lyase_beta_bac
TypeHelp Family
SignaturesHelp
InterPro RelationshipsHelp
Parent IPR011206 Citrate lyase, beta subunit
Contains IPR011076 Malate synthase-like, core
IPR015813 Pyruvate/Phosphoenolpyruvate kinase, catalytic core
GO Term annotationHelp
Process GO:0006084 acetyl-CoA metabolic process
Function GO:0008816 citryl-CoA lyase activity
Component GO:0005737 cytoplasm
GO:0009346 citrate lyase complex
InterPro annotation
BioMart Logo Entry Details in BioMart
AbstractHelp

This group of sequences represent the beta subunit of the holoenzyme citrate lyase (EC:4.1.3.6) composed of alpha (EC:2.8.3.10), beta, and acyl carrier protein subunits in a stoichiometric relationship of 6:6:6. Citrate lyase is an enzyme which converts citrate to oxaloacetate. In bacteria, this reaction is involved in citrate fermentation. The beta subunit catalyzes the reaction (3S)-citryl-CoA = acetyl-CoA + oxaloacetate. The group contains an experimentally characterised member from Leuconostoc mesenteroides [1]. The group contains sequences from a wide range of Gram-positive bacteria. For Gram-negative bacteria, it appears that only the sequences from gamma proteobacteria are present.

Database linksHelp
PRIAM: PRI000658

Taxonomic coverageHelp

Overlapping InterPro entriesHelp
IPR006475 Numbers of overlapping proteins Average numbers of overlapping amino acids

Example proteinsHelp
O53078 Citrate lyase subunit beta

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR006475 Citrate lyase, beta subunit, bacteria
IPR005000 HpcH/HpaI aldolase
IPR011076 Malate synthase-like, core
IPR015813 Pyruvate/Phosphoenolpyruvate kinase, catalytic core
IPR011206 Citrate lyase, beta subunit
SWISS-MODEL
ModBase

PublicationsHelp
1. Bekal S, Van Beeumen J, Samyn B, Garmyn D, Henini S, Divies C, Prevost H.
Purification of Leuconostoc mesenteroides citrate lyase and cloning and characterization of the citCDEFG gene cluster.
J. Bacteriol. 180 647-54 1998 [PubMed: 9457870]
http://ukpmc.ac.uk/picrender.cgi?tool=EBI&pubmedid=9457870&action=stream&blobtype=pdf

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InterPro 24.0