EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR006465 Glucoamylase

Protein matches Help

UniProtKB

Matches:

7 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR006465 Glucoamylase

Type

Family

Signatures Help

Database	ID	Name	Proteins
TIGRFAMs	TIGR01577	oligosac_amyl	7
Signatures in BioMart

InterPro Relationships Help

Contains

IPR011613 Glycoside hydrolase 15-related

InterPro annotation

Entry Details in BioMart

Abstract

This entry represents glycoamylase enzymes (also known as glucan 1,4-alpha-glucosidase), which catalyse the hydrolysis of terminal 1,4-linked alpha-D-glucose residues successively from non-reducing ends of the chains with the release of beta-D-glucose. This enzyme has been characterised in Thermoactinomyces vulgaris, where, unlike previously characterised glucoamylases, this enzyme hydrolyzes maltooligosaccharides (maltotetraose, maltose) more efficiently than starch, indicating this enzyme belongs to a class of glucoamylase-type enzymes with oligosaccharide-metabolizing activity [1, 2].

More information about this protein can be found at Protein of the Month: alpha-Amylase [3].

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR006465

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

Q59005 Uncharacterized glycosyl hydrolase MJ1610

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR012341	Six-hairpin glycosidase
IPR008928	Six-hairpin glycosidase-like
IPR011613	Glycoside hydrolase 15-related
IPR000165	Glycoside hydrolase, family 15
IPR006465	Glucoamylase
	SWISS-MODEL
	ModBase

Publications Open in usermanual
1.	Uotsu-Tomita R, Tonozuka T, Sakai H, Sakano Y. Novel glucoamylase-type enzymes from Thermoactinomyces vulgaris and Methanococcus jannaschii whose genes are found in the flanking region of the alpha-amylase genes. Appl. Microbiol. Biotechnol. 56 465-73 2001 [PubMed: 11549021] http://dx.doi.org/10.1007/s002530100609
2.	Ichikawa K, Tonozuka T, Mizuno M, Tanabe Y, Kamitori S, Nishikawa A, Sakano Y. Crystallization and preliminary X-ray analysis of Thermoactinomyces vulgaris R-47 maltooligosaccharide-metabolizing enzyme homologous to glucoamylase. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61 302-4 2005 [PubMed: 16511025] http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=EBI&pubmedid=16511025
3.	McDowall J. Protein of the Month ? alpha-Amylase. 2006

InterPro 23.1