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InterPro: IPR006425 Glucan 1,4-alpha-glucosidase

Protein matches Help

UniProtKB

Matches:

32 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR006425 Glucan_glucosid

Type

Family

Signatures Help

Database	ID	Name	Proteins
TIGRFAMs	TIGR01535	glucan_glucosid	32
Signatures in BioMart

InterPro Relationships Help

Contains

IPR011613 Glycoside hydrolase 15-related
IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup
IPR015220 Glucodextranase N

InterPro annotation

Entry Details in BioMart

Abstract

Glucan 1,4-alpha-glucosidase catalyzes the hydrolysis of terminal 1,4-linked alpha-D-glucose residues from non-reducing ends of polysaccharides, releasing a beta-D-glucose monomer. Some forms of this enzyme can hydrolyze terminal 1,6- and 1,3-alpha-D-glucosidic bonds in polysaccharides as well [1].

Structural links Help

PDB - click here

SCOP: a.102.1.5 , b.30.5.5

CATH: 1.50.10.10 , 2.70.98.10

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR006425

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P29761 Glucoamylase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR012341	Six-hairpin glycosidase
IPR006425	Glucan 1,4-alpha-glucosidase
IPR008928	Six-hairpin glycosidase-like
IPR015220	Glucodextranase N
IPR014718	Glycoside hydrolase-type carbohydrate-binding, subgroup
IPR011613	Glycoside hydrolase 15-related
IPR000165	Glycoside hydrolase, family 15
IPR011013	Glycoside hydrolase-type carbohydrate-binding
	SWISS-MODEL
	ModBase

Publications Open in usermanual
1.	Ohnishi H, Kitamura H, Minowa T, Sakai H, Ohta T. Molecular cloning of a glucoamylase gene from a thermophilic Clostridium and kinetics of the cloned enzyme. Eur. J. Biochem. 207 413-8 1992 [PubMed: 1633799] http://dx.doi.org/10.1111/j.1432-1033.1992.tb17064.x

Additional Reading Open in usermanual
	Mizuno M, Tonozuka T, Suzuki S, Uotsu-Tomita R, Kamitori S, Nishikawa A, Sakano Y. Structural insights into substrate specificity and function of glucodextranase. J. Biol. Chem. 279 2004 10575-83 [PubMed: 14660574] http://dx.doi.org/10.1074/jbc.M310771200
	Aleshin AE, Feng PH, Honzatko RB, Reilly PJ. Crystal structure and evolution of a prokaryotic glucoamylase. J. Mol. Biol. 327 2003 61-73 [PubMed: 12614608] http://dx.doi.org/10.1016/S0022-2836(03)00084-6

InterPro 23.1