EBI Databases InterPro	Search Open in usermanual InterPro:
Jump to: InterProScan Databases Documentation FTP site Help Click on the icon for context sensitive help from the user manual. Advanced search

InterPro: IPR006381 HAD-superfamily hydrolase, superfamily IIB, YedP

Protein matches Help

UniProtKB

Matches:

186 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR006381 HAD-SF_hydro_IIB_YedP

Type

Family

Signatures Help

Database	ID	Name	Proteins
TIGRFAMs	TIGR01486	HAD-SF-IIB-MPGP	186
Signatures in BioMart

InterPro Relationships Help

Parent

IPR006379 HAD-superfamily hydrolase, subfamily IIB

Children

IPR012813 Mannosyl-3-phosphoglycerate phosphatase
IPR012815 Mannosyl-3-phosphoglycerate phosphatase-related

Contains

IPR013200 HAD superfamily hydrolase-like, type 3

GO Term annotation Help

Process

GO:0008152 metabolic process

Function

GO:0050531 mannosyl-3-phosphoglycerate phosphatase activity

Component

GO:0005737 cytoplasm

InterPro annotation

Entry Details in BioMart

Abstract

This small group of proteins is a member of the IIB subfamily of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases (IPR005834). Nothing is known about the function of this group of proteins, however given that the other known enzymes of the IIB subfamily are sugar phosphatases or mutases, it would not be unreasonable to predict that these also acts on sugars.

Structural links Help

PDB - click here

SCOP: c.108.1.10

CATH: 3.30.980.20

Database links Help

Enzyme: EC:3.1.3.70

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR006381

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

O58690 Mannosyl-3-phosphoglycerate phosphatase

P76329 Putative mannosyl-3-phosphoglycerate phosphatase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR006379	HAD-superfamily hydrolase, subfamily IIB
IPR012815	Mannosyl-3-phosphoglycerate phosphatase-related
IPR012813	Mannosyl-3-phosphoglycerate phosphatase
IPR006381	HAD-superfamily hydrolase, superfamily IIB, YedP
IPR013200	HAD superfamily hydrolase-like, type 3
	PDB Chain
	ModBase
	CATH Domain
	SCOP Domain

Publications Help

Additional Reading Open in usermanual
	Empadinhas N, Albuquerque L, Henne A, Santos H, da Costa MS. The bacterium Thermus thermophilus, like hyperthermophilic archaea, uses a two-step pathway for the synthesis of mannosylglycerate. Appl. Environ. Microbiol. 69 2003 3272-9 [PubMed: 12788726] http://dx.doi.org/10.1128/AEM.69.6.3272-3279.2003
	Kawamura T, Watanabe N, Tanaka I. Structure of mannosyl-3-phosphoglycerate phosphatase from Pyrococcus horikoshii. Acta Crystallogr. D Biol. Crystallogr. 64 2008 1267-76 [PubMed: 19018103] http://dx.doi.org/10.1107/S0907444908033817

InterPro 23.1