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InterPro: IPR006232 Sucrose-6-phosphate hydrolase

Protein matches Help

UniProtKB

Matches:

550 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR006232 Suc6P_hydrolase

Type

Family

Signatures Help

Database	ID	Name	Proteins
TIGRFAMs	TIGR01322	scrB_fam	550
Signatures in BioMart

InterPro Relationships Help

Parent

IPR001362 Glycoside hydrolase, family 32

Contains

IPR013148 Glycosyl hydrolases family 32, N-terminal
IPR013189 Glycosyl hydrolase family 32, C-terminal
IPR018053 Glycoside hydrolase, family 32, active site

GO Term annotation Help

Process

GO:0005975 carbohydrate metabolic process

Function

GO:0004564 beta-fructofuranosidase activity

Component

GO:0005737 cytoplasm

InterPro annotation

Entry Details in BioMart

Abstract

O-Glycosyl hydrolases EC:3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [1, 2, 3]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site [4]. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in clans.

Glycoside hydrolase family 32 comprises enzymes with several known activities; invertase (EC:3.2.1.26); inulinase; levanase (EC:3.2.1.7); exo-inulinase (EC:3.2.1.7); sucrose:sucrose 1-fructosyltransferase (EC:3.2.1.7); and fructan:fructan 1-fructosyltransferase (EC:2.4.1.100). This subfamily represents sucrose-6-phosphate hydrolase.

Database links Help

Enzyme: EC:3.2.1.26

CAZy: GH32

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR006232

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

A1STJ9 Probable sucrose-6-phosphate hydrolase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013148	Glycosyl hydrolases family 32, N-terminal
IPR018053	Glycoside hydrolase, family 32, active site
IPR001362	Glycoside hydrolase, family 32
IPR013189	Glycosyl hydrolase family 32, C-terminal
IPR008985	Concanavalin A-like lectin/glucanase
IPR006232	Sucrose-6-phosphate hydrolase
	SWISS-MODEL

Publications Open in usermanual
1.	Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G. Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases. Proc. Natl. Acad. Sci. U.S.A. 92 7090-4 1995 [PubMed: 7624375] http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=7624375&action=stream&blobtype=pdf
2.	Davies G, Henrissat B. Structures and mechanisms of glycosyl hydrolases. Structure 3 853-9 1995 [PubMed: 8535779] http://dx.doi.org/10.1016/S0969-2126(01)00220-9
3.	Bairoch A. Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT. 1999
4.	Henrissat B, Coutinho PM. Carbohydrate-Active Enzymes server. 1999

InterPro 23.1