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InterPro: IPR005928 6-phospho-beta-galactosidase

Protein matches Help

UniProtKB

Matches:

195 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR005928 LacG

Type

Family

Signatures Help

Database	ID	Name	Proteins
TIGRFAMs	TIGR01233	lacG	195
Signatures in BioMart

InterPro Relationships Help

Parent

IPR001360 Glycoside hydrolase, family 1

Contains

IPR013781 Glycoside hydrolase, subgroup, catalytic core
IPR018120 Glycoside hydrolase, family 1, active site

GO Term annotation Help

Process

GO:0019512 lactose catabolic process via tagatose-6-phosphate

Function

GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds

InterPro annotation

Entry Details in BioMart

Abstract

6-phospho-beta-galactosidase (EC:3.2.1.85) is part of the tagatose-6-phosphate pathway of galactose-6-phosphate degradation.

A 6-phospho-beta-D-galactoside + H2O = an alcohol + 6-phospho-D-galactose

The genes coding for the enzymes of the tagatose 6-phosphate pathway have been found to be part of the lac operon together with the genes coding for the lactose-phosphotransferase system and the phospho-beta-galactosidase in Lactococcus lactis, Staphylococcus aureus, and Streptococcus mutans.

Structural links Help

PDB - click here

SCOP: c.1.8.4

CATH: 3.20.20.80

Database links Help

Enzyme: EC:3.2.1.85

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR005928

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P11546 6-phospho-beta-galactosidase

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013781	Glycoside hydrolase, subgroup, catalytic core
IPR018120	Glycoside hydrolase, family 1, active site
IPR001360	Glycoside hydrolase, family 1
IPR005928	6-phospho-beta-galactosidase
IPR017853	Glycoside hydrolase, catalytic core
	PDB Chain
	ModBase
	SCOP Domain
	CATH Domain

Publications Help

Additional Reading Open in usermanual
	Wiesmann C, Hengstenberg W, Schulz GE. Crystal structures and mechanism of 6-phospho-beta-galactosidase from Lactococcus lactis. J. Mol. Biol. 269 1997 851-60 [PubMed: 9223646] http://dx.doi.org/10.1006/jmbi.1997.1084
	Wiesmann C, Beste G, Hengstenberg W, Schulz GE. The three-dimensional structure of 6-phospho-beta-galactosidase from Lactococcus lactis. Structure 3 1995 961-8 [PubMed: 8535789] http://dx.doi.org/10.1016/S0969-2126(01)00230-1

InterPro 23.1