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InterPro: IPR005502 ADP-ribosylation/Crystallin J1

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1074 proteins

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Accession List
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Accession

IPR005502 Ribosyl_crysJ1

Type

Family

Signatures Help

Database	ID	Name	Proteins
Pfam	PF03747	ADP_ribosyl_GH	1032
SuperFamily	SSF101478	Ribosyl_crysJ1	1064
Signatures in BioMart

InterPro Relationships Help

Children

IPR012108 ADP-ribosylarginine hydrolase
IPR013479 ADP-ribosyl-dinitrogen reductase hydrolase

InterPro annotation

Entry Details in BioMart

Abstract

This family includes enzymes that perform ADP-ribosylations, such as ADP-ribosylarginine hydrolase EC:3.2.2.19 which cleaves ADP-ribose-L-arginine [1]. The family also includes dinitrogenase reductase activating glycohydrolase [2], and most surprisingly jellyfish crystallins [2], although these proteins appear to have lost the presumed active site residues.

Structural links Help

PDB - click here

SCOP: a.209.1.1

Database links Help

PANDIT: PF03747

Blocks: IPB005502

Taxonomic coverage Help

Overlapping InterPro entries Help

IPR005502

Numbers of overlapping proteins

Average numbers of overlapping amino acids

Example proteins Help

P14300 ADP-ribosyl-[dinitrogen reductase] glycohydrolase

Q02589 [Protein ADP-ribosylarginine] hydrolase

Q5UQA6 Putative ADP-ribosyl glycohydrolase L543

Q8CG72 Poly(ADP-ribose) glycohydrolase ARH3

Q9NX46 Poly(ADP-ribose) glycohydrolase ARH3

More proteins

Example Proteins Key

InterPro entry accession number/name and structure databases		Colour code
IPR013479	ADP-ribosyl-dinitrogen reductase hydrolase
IPR005502	ADP-ribosylation/Crystallin J1
IPR012108	ADP-ribosylarginine hydrolase
	SWISS-MODEL
	PDB Chain
	ModBase

Publications Open in usermanual
1.	Takada T, Iida K, Moss J. Cloning and site-directed mutagenesis of human ADP-ribosylarginine hydrolase. J. Biol. Chem. 268 17837-43 1993 [PubMed: 8349667] http://intl.jbc.org/cgi/content/abstract/268/24/17837
2.	Fitzmaurice WP, Saari LL, Lowery RG, Ludden PW, Roberts GP. Genes coding for the reversible ADP-ribosylation system of dinitrogenase reductase from Rhodospirillum rubrum. Mol. Gen. Genet. 218 340-7 1989 [PubMed: 2506427] http://dx.doi.org/10.1007/BF00331287

Additional Reading Open in usermanual
	Piatigorsky J, Horwitz J, Norman BL. J1-crystallins of the cubomedusan jellyfish lens constitute a novel family encoded in at least three intronless genes. J. Biol. Chem. 268 1993 11894-901 [PubMed: 8505315] http://intl.jbc.org/cgi/reprint/268/16/11894.pdf

InterPro 23.1