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InterPro: IPR005201 Glycoside hydrolase, family 85

Protein matchesHelp
UniProtKB
Matches:
171 proteins
AccessionHelp IPR005201 Glyco_hydro_85
TypeHelp Domain
SignaturesHelp
GO Term annotationHelp
Function GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity
Component GO:0005737 cytoplasm
InterPro annotation
BioMart Logo Entry Details in BioMart
AbstractHelp

O-Glycosyl hydrolases EC:3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [1, 2, 3]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site [4]. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in clans.

This group of endo-beta-N-acetylglucosaminidases belong to the glycoside hydrolase family 85 (GH85). These enzymes work on a broad spectrum of substrates.

Database linksHelp
Enzyme: EC:3.2.1.96
CAZy: GH85
PANDIT: PF03644

Taxonomic coverageHelp

Example proteinsHelp
A1L251 Cytosolic endo-beta-N-acetylglucosaminidase

Q8BX80 Cytosolic endo-beta-N-acetylglucosaminidase

Q8NFI3 Cytosolic endo-beta-N-acetylglucosaminidase

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR005201 Glycoside hydrolase, family 85
IPR001357 BRCT
ModBase

PublicationsHelp
1. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G.
Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.
Proc. Natl. Acad. Sci. U.S.A. 92 7090-4 1995 [PubMed: 7624375]
http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=7624375&action=stream&blobtype=pdf
2. Davies G, Henrissat B.
Structures and mechanisms of glycosyl hydrolases.
Structure 3 853-9 1995 [PubMed: 8535779]
http://dx.doi.org/10.1016/S0969-2126(01)00220-9
3. Bairoch A.
Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT.
1999
4. Henrissat B, Coutinho PM.
Carbohydrate-Active Enzymes server.
1999

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InterPro 23.1