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InterPro: IPR005198 Glycoside hydrolase, family 76

Protein matchesHelp
UniProtKB
Matches:
459 proteins
AccessionHelp IPR005198 Glyco_hydro_76
TypeHelp Family
SignaturesHelp
InterPro RelationshipsHelp
Children IPR014480 Mannan endo-1,6-alpha-mannosidase
IPR014512 Predicted O-glycosyl hydrolase
Contains IPR008928 Six-hairpin glycosidase-like
InterPro annotation
BioMart Logo Entry Details in BioMart
AbstractHelp

O-Glycosyl hydrolases EC:3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [1, 2, 3]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site [4]. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in clans.

This is a family of alpha-1,6-mannanases belonging to glycoside hydrolase family 76 (GH76).

Database linksHelp
Enzyme: EC:3.2.1.101
CAZy: GH76
PANDIT: PF03663

Taxonomic coverageHelp

Overlapping InterPro entriesHelp
IPR005198 Numbers of overlapping proteins Average numbers of overlapping amino acids

Example proteinsHelp
O14131 Meiotically up-regulated gene 191 protein

P36091 Mannan endo-1,6-alpha-mannosidase DCW1

More proteins


Example Proteins Key


InterPro entry accession number/name and structure databases Colour code
IPR014480 Mannan endo-1,6-alpha-mannosidase
IPR005198 Glycoside hydrolase, family 76
IPR008928 Six-hairpin glycosidase-like
ModBase

PublicationsHelp
1. Henrissat B, Callebaut I, Fabrega S, Lehn P, Mornon JP, Davies G.
Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.
Proc. Natl. Acad. Sci. U.S.A. 92 7090-4 1995 [PubMed: 7624375]
http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=7624375&action=stream&blobtype=pdf
2. Davies G, Henrissat B.
Structures and mechanisms of glycosyl hydrolases.
Structure 3 853-9 1995 [PubMed: 8535779]
http://dx.doi.org/10.1016/S0969-2126(01)00220-9
3. Bairoch A.
Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT.
1999
4. Henrissat B, Coutinho PM.
Carbohydrate-Active Enzymes server.
1999

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InterPro 23.1