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InterPro: IPR005130 Serine dehydratase alpha chain

Protein matches Help

UniProtKB

Matches:

1718 proteins

Overview:	sorted by AC,	sorted by name,	of known structure,	proteins with splice variants
Detailed:	sorted by AC,	sorted by name,	of known structure	proteins with splice variants
Table:	For all matching proteins,	of known structure
Architectures
Accession List
Matches in BioMart

Accession

IPR005130 Ser_deHydtase_asu

Type

Domain

Signatures Help

Database	ID	Name	Proteins
Pfam	PF03313	SDH_alpha	1718
Signatures in BioMart

InterPro Relationships Help

Found in

IPR004642 L-serine dehydratase, alpha subunit
IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form

GO Term annotation Help

Process

GO:0006094 gluconeogenesis

Function

GO:0003941 L-serine ammonia-lyase activity
GO:0051539 4 iron, 4 sulfur cluster binding

InterPro annotation

Entry Details in BioMart

Abstract

L-serine dehydratase is found as a heterodimer of alpha and beta chain or as a fusion of the two chains in a single protein. This enzyme catalyses the deamination of serine to form pyruvate. This enzyme is part of the gluconeogenesis pathway.

Database links Help

Enzyme: EC:4.3.1.17

PANDIT: PF03313

Blocks: IPB005130

CluSTr: ALLvsALL:35226:47.8

Taxonomic coverage Help